Saussurea

Related Terms

1,5-Dihydroxypinoresinol-4'-O-beta-D-glucopyranoside, 1alpha-hydroxy-2alpha,4alpha-guaicyl-3,7-dioxabicyclo[3.3.0]octane, 1beta,3beta-dihydroxyursa-9(11),12-diene-3-octadecanoate, 1beta-hydroxy arbusculin A, (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside, (+)-1-hydroxypinoresinol-1-O-beta-D-glucoside, 1-hydroxy-(Z)-3-hexene-2,5-dione, 2,4-dimethyl-4-hydroxy-2-butenolide,3-hexene-2,5-dione, 2alpha-guaicyl-4-oxo-6alpha-catechyl-3,7-dioxabicyclo[3.3.0]octane, 2-methoxy-4-(2-propenyl)phenyl beta-D-glucoside, (2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-2-(5-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-tetrahydrofuran-3-ol, 3',5'-dimethoxy apigenin, 3,5-dimethoxy-4-hydroxyacetophenone, 3,5-dimethoxy-4-hydroxy-benzaldehyde, 3alpha,22alpha-diacetoxy-20beta,21alpha,29-trihydroxy-30-norolean-12-ene, 3alpha,22alpha-diacetoxy-20beta,21alpha-dihydroxy-29-palmityloxy-30-norolean-12-ene, 3alpha,22alpha-diacetoxy-21alpha,29-dihydroxy-20beta-methoxy-30-norolean-12-ene, 3alpha-(E)-caffeoyloxyolean-12-en-30-oic acid, 3alpha-(E)-coumaroyloxyolean-12-en-30-oic acid, 3alpha-hydroxy-5,6-epoxy-7-megastigmen-9-one, 3alpha-hydroxy-11alphaH-guaia-4(15),10(14)-diene-12,6alpha-olide, 3alpha-hydroxyl-11beta,13-dihydrodehydrocostuslactone-8-O-beta-D-glucoside, 3beta,8alpha-dihydroxy-13-methoxyl-4(14),10(15)-dien-(1alphaH,5alphaH,6beta H,11alphaH)-12,6-olide, 3beta,8alpha-dihydroxy-13-methoxyl-4(14),10(15)-dien-(1alphaH,5alphaH,6beta H,11betaH)-12,6-olide, 3beta,22alpha-dihydroxyolean-12-en-30-oic acid, 3beta-hydroxy-5alpha,6alpha-epoxy-7-megastigmen-9-one, 3beta-hydroxy-8alpha-epoxymethylacriloiloxy-4(15),10(14),11(13)-trien-guaian-6,12-olide, 3-hydroxyhexane-2,5-dione, 3-O-beta-D-fucopyranosylstrophanthidin, 3-O-beta-D-glucopyranosyl-(1-->4)-alpha-L-rhamnopyranosylcannogenin, 3-O-beta-D-quinovopyranosylperiplogenin, (3S)-3-O-(3',4'-diangeloyl-beta-D-glucopyranosyloxy)-3,7-trimethylocta-1,6-diene, 3-stigmastanol, 4,6-decadiyne-1-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside, 4,6-decadiyne-1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside, 4(15)- eudesmene-1beta,6alpha-diol, 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, 4-allyl-2,6-dimethoxyphenyl glucoside, 4-hydroxy cinnamic acid, (4R,7R*/S*)-2,4-dimethyl-4-(1'-acetyl-3'-oxobutyl)-2-butenolide, (4R,7S*/R*)-2,4-dimethyl-4-(1'-acetyl-3'-oxobutyl)-2-butenolide, 5-hydroxy-7-methoxy coumarin, 5-hydroxymethyl-furaldehyde, 6''-O-crotonoylhomoplantaginin, 7delta-methoxy-4(14)-oppositen-1beta-ol, 7-dihydroxy-2-methylchromone, 7-hydroxy coumarin, 7'-hydroxyiso-lappaol A, 7-methoxykaempferol 3-O-alpha-L-rhamnopyranoside, 7-O-[alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside], (7'R,8'R)-2,2'-dimethoxy-4-(3-hydroxyl-propenyl)-4'-(1,2,3-trihydroxypropyl)-biphenyl ether, (7S,8R,8'R)-5,5'-dimethoxylariciresinol, 8alpha-acetoxydehydrocostus lactone, 8alpha-hydroxy-11alpha,13-dihydrozaluzanin C, 8alpha-hydroxy-11beta-11,13-dihydrodehydrocostuslactone, 8alpha-hydroxypinoresinol, 8alpha-O-(2', 3'-dihydroxyisobutyryl)11beta,13-dihydrodesacylcynaropicrin, 8alpha-O-(3'-hydroxy-3'-methylbutyryl)desacylcynaropicrin, (8E)-decaene-4,6-diyn-1-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside, 8-hydroxyzaluzanin C, (8Z)-decaene-4,6-diyn-1-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside, 11,12,13-trihydroxy-4(15),8-eudesmadiene-9-one, (+)-11alpha,13-dihydrodehydrocostus lactone, 11,13beta-dihydrozaluzanin C, 11beta,13-dihydrocostunolide, 11beta,13-dihydrodehydrocostuslactone-8-O-[6'-O-acetyl-beta-D-glucoside], 11beta,13-dihydrodehydrocostuslactone-8-O-beta-D-glucoside, 11beta-H-2 alpha-hydroxy-eudesman-4(15)-en-12,8-beta-olide, 13-epi-phaeophorbide-a, 13-epi-phaeophorbide-a methyl ester, 13-sulfo-dihydrodehydrocostus lactone, 13-sulfo-dihydroreynosin, 13-sulfo-dihydrosantamarine, 20alpha,21alpha-epoxy-taraxastane-3beta,22alpha-diol, 22-oxo-20-taraxasten-3beta-ol, aloe-emodin-8-O-beta-D-glucopyranoside, alpha-cyclocostunolide, amarantholidol A glycoside, amarantholidoside IV, amino acids, apigenin, apigenin 7-glucoside, apigenin 7-lutinoside, apigenin 7-O-beta-D-glucoside, apigenin glucosides, apigenin lutinosides, arbusculin A, arctigenin, arctigenin 4-O-(2''-O-acetyl-beta-D-glucoside), arctigenin 4-O-(3''-O-acetyl-beta-d-glucoside), arctigenin 4-O-(6''-O-acetyl-beta-d-glucoside), arctiin, arguerin B, aristocholic acid, asebotin, Asteraceae (family), auklandia, austricin, beta-amirenol, beta-amirenyl acetate, beta-costic acid, beta-cyclocostunolide, (-)-beta-elemene, beta-sitosterol, betulinic acid, betulinic acid methyl ester, butenolide derivatives, calcium, caffeoylquinic acids, cardenolides, cebellin F, ceramides, chlorogenic acid, chlorohyssopifolin A, chlorohyssopifolin E, chlorohyssopifolins, chlorojanerin, chrysophanol, conicaol A, conicaol B, conicaosides, copper, costal, costic acid, costic oil, costic root oil, costol, costunolide-15-O-beta-D-glucopyranoside, costunolides, costus, costus absolute, Costus tapenbeckianus, Costus woodsonii, cynaropicrin, dammarane triterpenoid, daucosterol, dehydrocostus lactone, desacylcynaropicrin, dihydrocostunolide, dotriacontanoic acid, (-)-elema-1,3,11(13)-trien-12-al, elema-1,3,11(13)-trien-12-oic acid, (-)-elema-1,3,11(13)-trien-12-ol, emodin, encelin, ent-labdane diterpenoid, ergostan-3,24-diol, ethyl 2-pyrrolidinone-5(s)-carboxylate, eudesman-8beta,12-olide-1-O-beta-D-glucoside, eudesmane-type sesquiterpenoids, flavones, flavonoid glycosides, flavonoids, fraxiresinol-4'-O-beta-D-glucopyranoside, gamma-linolenic acid, gerin and derivatives, germacra-1(10),4,11(13)-trien-12-al, germacra-1(10),4,11(13)-trien-12-oic acid, germacra-1(10),4,11(13)-trien-12-ol, (+)-germacrene A, germacrenes, glucose, guaianolides, heptadec-(9Z)-enoic acid, hexacosan-4-olide, Himalayan snowball plants, hispidulin, hydroxypropiophenone, inulin, iron, isoscopoletin, jaceosidin, kaempferol 3-O-alpha-L-rhamnopyranoside, kaempferol 3-O-beta-D-glucopyranoside, kaempferol 3-O-beta-D-glucoside, kaempferol glucosides, kandavanolide, Kangen-karyu, khushta, kushta, kust, kuth, lignan glycosides, lignans, linalyl-O-beta-D-glucoside, luteolin, luteolin 7-O-beta-D-glucoside, magnesium, magnolialide, manganese, (-)-massoniresinol 4"-O-beta-D-glucopyranoside, matairesinol, medusaside A, medusaside B, methyl-3-(2',4'-dihydroxyphenyl) propanoate, methyl-5-caffeoylquinic acid, mokko lactone, mu xiang (Chinese), neoechinulin A, oleanane-type triterpenes, oliganthas A, oliganthas B, (-)-olivil-4''-O-beta-D-glucopyranoside, (-)-oplopan-4-one-10alpha-O-beta-D-glucoside, padma28, palmitic acid, patchak, phenolic glucosides, p-hydroxybenzaldehyde, polysaccharides, potassium, ptiloepoxide, pulchellamine A, pulchellamine B, pulchellamine C, pulchellamine D, pulchellamine E, pulchellamine F, pulchellamine G, qinghai, quang my xiang (Chinese), quercetin 3-O-alpha-L-rhamnopyranoside, quercetin 3-O-beta-D-glucopyranoside, quercetin glucosides, quinic acid derivatives, Qust-e-Shereen, radix Aucklandia, reynosin, rhein-8-O-beta-D-glucopyranoside, rutin, S. abnormis, S. acromelaena, S. acrophila, S. acropilina, S. acroura, S. acuminate, S. aegirophylla, S. affinis, S. ainorum, S. alaschanica, S. alata, S. alatipes, S. albescens, S. albescens var. incisifolia, S. alpicola, S. alpina (Alpine saw-wort), S. alpina densa, S. alpina depressa, S. alpina esthonica, S. alpina var. densa, S. amabilis, S. amara (Saussurea), S. ambigua, S. amblyophylla, S. americana (American saw-wort), S. amoena, S. amurensis, S. andersonii, S. andryaloides, S. angustifolia (narrow-leaved saw-wort), S. angustifolia var. angustifolia (narrowleaf saw-wort), S. angustifolia var. viscida, S. angustifolia var. yukonensis (narrowleaf saw-wort), S. angustifolia yukonensis (narrowleaf saw-wort), S. anochaete, S. apus, S. arenaria, S. aspera, S. aster, S. atkinsonii, S. atriplicifolia, S. auriculata, S. baicalensis, S. bella, S. bhutkesh, S. blanda, S. bodinieri, S. brachycephala, S. brachylepis, S. bracteata, S. brunneopilosa, S. bullata, S. bullockii, S. bungei, S. caerulea, S. caespitosa, S. calcicola, S. cana, S. candicans, S. candolleana, S. canescens, S. caprifolia, S. carduiformis, S. carthamoides, S. catharinae, S. caudate, S. cauloptera, S. ceratocarpa, S. ceratocarpa var. depressa, S. ceterach, S. ceterachifolia, S. chabyoungsanica, S. chamarensis, S. chenopodifolia, S. chenopodiifolia, S. chinensis, S. chingiana, S. chinnampoensis, S. chinnampoensis var. gracile, S. chionophora, S. chionophylla, S. chitralica, S. chrysotricha, S. ciliaris, S. cirsium, S. clarkei, S. cochlearifolia, S. coerulea, S. columnaris, S. conandrifolia, S. congesta, S. conica, S. controversa, S. controversa f. sinuate, S. conyzoides, S. cordifolia, S. coronata, S. costus, S. costus (Falc.) Lipschitz, S. crassifolia, S. crispa, S. decurrens, S. delavayi, S. deltoidea, S. deltoides, S. densa (clustered saw-wort), S. denticulate, S. depressa, S. depsangensis, S. dhwojii, S. diamantiaca, S. diamantica, S. dielsiana, S. discolor, S. dolichopoda, S. donkiah, S. dubia, S. duiensis, S. dutaillyana, S. dzeurensis, S. edulis, S. elata, S. elegans, S. elliptica, S. elongate, S. eopygmaea, S. epilobioides, S. eriocephala, S. eriolepis, S. eriophylla, S. erubescens, S. esthonica, S. euodonta, S. falconeri, S. fastuosa, S. fauriei, S. firma, S. fistulosa, S. flexuosa, S. foliosa, S. formosana, S. forrestii, S. franchetii, S. frolowii, S. frondosa, S. fruticulosa, S. fulcrata, S. georgei, S. gilesii, S. glacialis, S. glanduligera, S. glandulosa, S. globosa, S. glomerata, S. gnaphalodes, S. gossipiphora, S. gossypina, S. gossypiphora, S. gossypiphora D.Don, S. gracilis, S. graminea, S. graminifolia, S. grandiflora, S. grandifolia, S. grosseserrata, S. grubovii, S. henryi, S. heteromalla, S. hieracioides, S. hookeri, S. hultenii, S. humilis, S. hylophila, S. hypargyrea, S. hypoleuca, S. hypsipeta, S. inaensis, S. inconspicua, S. insularis, S. intermedia, S. involucrata, S. involucrata Kar. et Kir., S. involucrata (Kar. et Kir.) Sch.Bip., S. iodostegia, S. irregularis, S. jacea, S. japonica, S. kansuensis, S. kanzanensis, S. karelinii, S. katochaete, S. katochaetoides, S. kingii, S. kiraisanensis, S. kiraisiensis, S. kirigaminensis, S. kitamurana, S. klementzii, S. koidzumiana, S. kolesnikovii, S. komaroviana, S. koslowii, S. kudoana, S. kunthiana, S. kurentzoviae, S. kurilensis, S. kwangtungensis, S. laciniata, S. lacostei, S. laminamaensis, S. lamprocarpa, S. lancifolia, S. lanicaulis, S. laniceps, S. laniceps Hand.-Mazz, S. lanuginose, S. lappa, S. lappa C.B.Clarke, S. lappa Decne., S. latifolia, S. lavrenkoana, S. leiocarpa, S. lenensis, S. leontodontoides, S. leptolepis, S. leucoma, S. leucophylla, S. lhunzhubensis, S. licentiana, S. likiangensis, S. limprichtii, S. linearifolia, S. lipschitzii, S. longifolia, S. loriformis, S. lyrata, S. lyratifolia, S. macrolepis, S. macrophylla, S. macrota, S. mairei, S. mandshurica, S. masarica, S. maximowiczii, S. medusa, S. medusa Maxim., S. melanotricha, S. minuta, S. modesta, S. mongolica, S. monocephala, S. montana, S. monticola, S. muliensis, S. mutabilis, S. myokoensis, S. namikawae, S. neglecta, S. nematolepis, S. neofranchetii, S. neopulchella, S. neoserrata, S. nepalensis, S. nidularis, S. nigrescens, S. nikoensis, S. nimborum, S. nipponica, S. nipponica var. yakusimensis, S. nishiokae, S. nivea, S. nomurae, S. nuda (chaffless saw-wort), S. nutans, S. obvallata, S. obvallata (DC.) Edgew., S. ochrochlaena, S. odontolepis, S. oligantha, S. oligantha Franch., S. orgaadayi, S. otophylla, S. ovata, S. oxyodonta, S. pachyneura, S. pallidiceps, S. pamirica, S. parviflora, S. paucijuga, S. paxiana, S. pectinata, S. pectinata f. macrocephala, S. peguensis, S. peipingensis, S. pennata, S. petrovii, S. phaeantha, S. phyllocephala, S. pilinophylla, S. pinetorum, S. piptathera, S. platyphyllaria, S. pohlei, S. polycephala, S. polycolea, S. polylepis, S. polypodioides, S. polystichoides, S. poochlamys, S. poophylla, S. popovii, S. populifolia, S. porcii, S. porphyroleuca, S. pricei, S. przewalskii, S. pseudoangustifolia, S. pseudo-gracilis, S. pseudosalsa, S. pseudosquarrosa, S. pseudo-tilesii, S. pteridophylla, S. pubifolia, S. pujolica, S. pulchella, S. pulvinata, S. pulvinata (Hook. et Grev.) Maximo, S. pumila, S. purpurascens, S. pycnocephala, S. pygmaea, S. quercifolia, S. ramose, S. rectinervis, S. recurvata, S. rhytidocarpa, S. riederi, S. riederii, S. robusta, S. rockii, S. romuleifolia, S. rorinsanensis, S. roylei, S. runcinata, S. sachalinensis, S. sacra, S. sagitta, S. saichanensis, S. sajanensis, S. salicifolia, S. salsa, S. salwinensis, S. sawadae, S. saxatilis, S. scabrida, S. scaposa, S. schanginiana, S. schultzii, S. sclerolepis, S. semilyrata, S. seoulensis, S. sericea, S. serrata, S. serratuloides, S. setidens, S. setifolia, S. sieboldiana, S. sikokiana var. sessiliflora, S. simpsoniana, S. sinuate, S. sinuatoides, S. sobarocephala, S. soczavae, S. sordida, S. sorocephala, S. sovietica, S. spathulifolia, S. spatulifolia, S. spicata, S. splendida, S. squarrosa, S. stafleuana, S. stella, S. stenolepis, S. stoliczkae, S. stracheyana, S. stricta, S. subacaulis, S. subsinuata, S. subtriangulata, S. subulata, S. subulisquama, S. sudhanshui, S. sughoo, S. sukaczevii, S. sungpanensis, S. superba, S. sylvatica, S. tanakae, S. tanakae var. intermedia, S. tanguensis, S. tangutica, S. taquetii, S. taraxacifolia, S. tatsienensis, S. thomsonii, S. thoroldii, S. tianshuiensis var. huxianensis, S. tibetica, S. tilesii (Tiles' Saussurea), S. tomentosa, S. topkegolensis, S. triangulata, S. tridactyla, S. triptera, S. tschuktschorum (Tschuktsch's Saussurea), S. tunicate, S. turgaiensis, S. uchiyamana, S. uliginosa, S. umbrosa, S. uniflora, S. ussuriensis, S. veitchiana, S. velutina, S. venosa, S. viscida (sticky saw-wort), S. wardii, S. weberi (Weber's saw-wort), S. wellbyi, S. wernerioides, S. wettsteiniana, S. woodiana, S. yabulaiensis, S. yakla, S. yanagisawae, S. yatagaiana, S. yesoensis var. angustifolia, S. yoshinagae, S. yunnanensis, santamarine, Saussurea costus (Flac.) Lipschitz, Saussurea lappa C.B.Clarke, Saussurea lappa roots, Saussureae radix, saussureamine A, saussureamine B, saussureamine C, saussureamine D, saussureamine E, saussureoside A, saussureoside B, scopoletin, scopolin, selaginellin, selinene, sesquiterpene glucosides, sesquiterpene lactones, sesquiterpenoids, shikokiols, snow lotus, sodium, stigmast-5-en-3beta,7alpha,22-triol, stigmast-7-en-3-ol, succinic acid, sulfocostunolide A, sulfocostunolide B, (+)-syringaresinol, syringin, taraxast-20(30)ene-3beta,21alpha-diol, taraxast-20(30)-ene-3beta-ol, taraxast-20-ene-3beta,30-diol, taraxast-20-ene-3beta-ol, taraxastane triterpenoids, taraxastane-3beta,20alpha-diol, trachelogenin, triterpenic pentacyclic compounds, umbelliferone, umbelliferonglucoside, wild saussurea, xuelian, xuelianlactone, xuelianlactone 8-O-beta-D-glcuoside, zaluzanin C, zinc.
Select combination products: Xue Lianhua (Saussurea involucrata, S. medusa, S. gossypiphora, S. polylada, S. laniceps, S. tridactyla, S. gnaphaloides, S. kingii, S. obvallata, S. tangutica, S. globosa, S. longifolia, Soroseris erysimoides, So. glomerata, and So. umbrella); Eazmov (Ayurvedic herbal preparation containing Cyperus rotundus, Tinosporda cordifolia, Saussurea lappa, Picrorrhiza kurrow, and Zingiber officiniale); Kangen-karyu (peony root, cnidium rhizome, safflower, cyperus rhizome, saussurea root (JP XIV), and Salvia miltiorrhiza root).

Background

Saussurea is used in traditional Chinese herbal medicines, as well as traditional medicine in Korean, Tibetan, Indian, Uighur, Pakistani, and Mongolian cultures.
The root, called costus root, is used to make a drug called aucklandia or mu xiang. In parts of Asia, the root is smoked in place of opium. It is also used as a spice and as incense, as well as to protect fabric from moths.
Extracts of costus, as well as many species of saussurea, are used to prevent muscle spasms, increase airflow in the lungs, lower blood pressure, reduce inflammation, and protect the nerves and stomach.
Saussurea has been studied for its possible effects on arthritis, asthma, stomach problems, and parasites. However, reliable evidence supporting the use of saussurea for any medical condition is lacking at this time.

Evidence Table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. GRADE *
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. GRADE *


Early evidence suggests that Saussurea lappa may lack an effect on arthritis. More research is needed before conclusions can be made.

 C


Early evidence suggests that Saussurea lappa may lack an effect on arthritis. More research is needed before conclusions can be made.

 C


Evidence supporting the use of saussurea for asthma is lacking. More research is needed before conclusions can be made.

 C


Evidence supporting the use of saussurea for asthma is lacking. More research is needed before conclusions can be made.

 C


Early research suggests that healthy people who take saussurea by mouth may experience a shorter time for food in the stomach to reach the small intestine, as well as higher levels of a protein that stimulates the gut muscle to contract. However, there was a lack of effect in people who had gastritis (inflammation of the stomach lining). More research is needed.

 C


Early research suggests that healthy people who take saussurea by mouth may experience a shorter time for food in the stomach to reach the small intestine, as well as higher levels of a protein that stimulates the gut muscle to contract. However, there was a lack of effect in people who had gastritis (inflammation of the stomach lining). More research is needed.

 C


Early research suggests that saussurea may protect against parasites in children. More research is needed before conclusions can be made.

 C


Early research suggests that saussurea may protect against parasites in children. More research is needed before conclusions can be made.

 C
* Key to grades

A: Strong scientific evidence for this use
B: Good scientific evidence for this use
C: Unclear scientific evidence for this use
D: Fair scientific evidence for this use (it may not work)
F: Strong scientific evidence against this use (it likley does not work)
* Key to grades

A: Strong scientific evidence for this use
B: Good scientific evidence for this use
C: Unclear scientific evidence for this use
D: Fair scientific evidence for this use (it may not work)
F: Strong scientific evidence against this use (it likley does not work)

Tradition / Theory

The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.

Dosing

Adults (18 years and older)
Saussurea has been taken by mouth as a tea or as tablets. Saussurea has also been given under the skin.

Safety

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

Interactions

Interactions with Drugs
Saussurea may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants (blood thinners) such as warfarin (Coumadin?) or heparin, antiplatelet drugs such as clopidogrel (Plavix?), and nonsteroidal anti-inflammatory drugs such as ibuprofen (Motrin?, Advil?) or naproxen (Naprosyn?, Aleve?).
Saussurea may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. People taking insulin or drugs for diabetes by mouth should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Saussurea may cause low blood pressure. Caution is advised in people taking drugs that lower blood pressure.
Saussurea may also interact with agents that may affect the blood, agents that may affect the immune system, agents that may affect the nervous system, agents that may affect the skin, agents that may affect the liver, agents that may improve exercise performance, agents that may treat anxiety, agents that may treat heart disorders, agents that may affect the kidney, agents that may treat stomach disorders, agents that may treat ulcers and reduce stomach acid, agents that may stimulate the uterus, antibiotics, anticancer agents, antifungals, anti-inflammatory agents, antiparasitics, antivirals, cholesterol-lowering agents, pain relievers, scopolamine, ticlopidine, and warfarin.

Attribution

This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).

Bibliography

Chen Q, Jiang P, Zhao J. Measurement of total flavone content in snow lotus (Saussurea involucrate) using near infrared spectroscopy combined with interval PLS and genetic algorithm. Spectrochim.Acta A Mol.Biomol.Spectrosc. 2010;76(1):50-55.
Chen RD, Zou JH, Jia JM, et al. Chemical constituents from the cell cultures of Saussurea involucrata. J Asian Nat.Prod.Res 2010;12(2):119-123.
Hsiao WL and Liu L. The role of traditional Chinese herbal medicines in cancer therapy--from TCM theory to mechanistic insights. Planta Med 2010;76(11):1118-1131.
Li G, Sun Z, Song C, et al. A sensitive fluorescence reagent, 2-[2-(7H-dibenzo[a,g]carbazol-7-yl)-ethoxy]ethyl chloroformate, for amino acids determination in Saussurea involucrate and Artemisia capillaris Thunb using high-performance liquid chromatography with fluorescence detection and identification with mass spectroscopy/electrospray ionization source. Biomed.Chromatogr. 2011;25(6):689-696.
Li XW, Guo ZT, Zhao Y, et al. Chemical constituents from Saussurea cordifolia. Phytochemistry 2010;71(5-6):682-687.
Lin YC, Hung CM, Tsai JC, et al. Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMP-activated protein kinase (AMPK). J Agric.Food Chem. 9-8-2010;58(17):9511-9517.
Liu YD and Aisa HA. Three new lignans from the seeds of Saussurea involucrata. J Asian Nat.Prod.Res 2010;12(10):828-833.
Nguyen DT, Gopfert JC, Ikezawa N, et al. Biochemical conservation and evolution of germacrene A oxidase in asteraceae. J Biol.Chem. 5-28-2010;285(22):16588-16598.
Qiu J, Xue X, Chen F, et al. Quality evaluation of snow lotus (Saussurea): quantitative chemical analysis and antioxidant activity assessment. Plant Cell Rep. 2010;29(12):1325-1337.
Shen S, Qian J, Ren J. Ethnoveterinary plant remedies used by Nu people in NW Yunnan of China. J Ethnobiol.Ethnomed. 2010;6:24.
Way TD, Lee JC, Kuo DH, et al. Inhibition of epidermal growth factor receptor signaling by Saussurea involucrata, a rare traditional Chinese medicinal herb, in human hormone-resistant prostate cancer PC-3 cells. J Agric.Food Chem. 3-24-2010;58(6):3356-3365.
Yang JL, Wang R, Liu LL, et al. Phytochemicals and biological activities of Saussurea species. J Asian Nat.Prod.Res 2010;12(2):162-175.
Yi T, Zhao ZZ, Yu ZL, et al. Comparison of the anti-inflammatory and anti-nociceptive effects of three medicinal plants known as "Snow Lotus" herb in traditional Uighur and Tibetan medicines. J Ethnopharmacol. 3-24-2010;128(2):405-411.
Yoo JH, Lee HJ, Kang K, et al. Lignans inhibit cell growth via regulation of Wnt/beta-catenin signaling. Food Chem.Toxicol. 2010;48(8-9):2247-2252.
Zhao Q, Yokozawa T, Yamabe N, et al. Kangen-karyu improves memory deficit caused by aging through normalization of neuro-plasticity-related signaling system and VEGF system in the brain. J Ethnopharmacol. 9-15-2010;131(2):377-385.