Allium ursinum

Bear's garlic/Drug Interactions:

  • Anti inflammatory agentsAnti inflammatory agents: Bear's garlic has demonstrated inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme (8). These findings suggest that bear's garlic has the potential to potentiate the activity of non-steroidal anti-inflammatory drugs.
  • Antiplatelet agentsAntiplatelet agents: Isolated compounds in bear's garlic have demonstrated inhibition of human platelet aggregation (1). Moreover, Bear's garlic demonstrated inhibitory activity on 5-lipoxygenase (LO), cyclooxygenase (CO), thrombocyte aggregation (TA), and angiotensin I-converting enzyme (ACE) (8). These findings suggest that bear's garlic has the potential to potentiate the activity of antiplatelet agents.

    • Bear's garlic/Herb/Supplement Interactions:

  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: Isolated compounds in bear's garlic have demonstrated inhibition of human platelet aggregation (1). Moreover, bear's garlic has shown inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme (8). These findings suggest that bear's garlic has the potential to potentiate the activity of herbs with antiplatelet activity.
  • Anti inflammatory herbsAnti inflammatory herbs: Bear's garlic has demonstrated inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme (8). These findings suggest that bear's garlic has the potential to potentiate the activity of herbs with anti-inflammatory activity.

    • Bear's garlic/Food Interactions:

  • Insufficient available evidence.

    • Bear's garlic/Lab Interactions:

  • Coagulation panelCoagulation panel: Isolated compounds in bear's garlic have demonstrated inhibition of human platelet aggregation (1; 8). Moreover, similar concentrations of S-containing compounds (thiosulfinates and ajoenes) and similar inhibitory activity on 5-lipoxygenase, cyclooxygenase, thrombocyte aggregation, and angiotensin I-converting enzyme were observed (8). These findings suggest that bear's garlic has the potential to impact coagulation panel results.