Bitter root

Gentian/Drug Interactions:

  • AlcoholAlcohol: According to secondary sources, some gentian preparations may contain alcohol, and concurrent use may cause additive effects.
  • Antidepressants, monoamine oxidase inhibitors (MAOIs)Antidepressants, monoamine oxidase inhibitors (MAOIs): According to laboratory evidence, gentisin and isogentisin from Gentiana lutea may potently inhibit monoamine oxidase types A and B (10). Three monoamine oxidase inhibitors isolated from Gentiana lutea have displayed competitive MAO inhibition more effectively against MAO-B than against MAO-A (11).
  • AntidiabeticsAntidiabetics: According to secondary sources, some gentian preparations may contain sugar and may interfere with blood sugar control.
  • AntifungalsAntifungals: According to animal evidence, Gentiana lutea extract may protect against reproductive toxicity when administered concurrently with ketoconazole-like agents (6).

    • Gentian/Herb/Supplement Interactions:

  • Antidepressants, monoamine oxidase inhibitors (MAOIs)Antidepressants, monoamine oxidase inhibitors (MAOIs): According to laboratory evidence, gentisin and isogentisin from Gentiana lutea may potently inhibit monoamine oxidase types A and B (10). Three monoamine oxidase inhibitors isolated from Gentiana lutea have displayed competitive MAO inhibition more effectively against MAO-B than against MAO-A (11).
  • AntifungalsAntifungals: According to animal evidence, Gentiana lutea extract may protect against reproductive toxicity when administered concurrently with ketoconazole-like agents (6).
  • HypoglycemicsHypoglycemics: According to secondary sources, some gentian preparations may contain sugar and may interfere with hypoglycemic agents.

    • Gentian/Food Interactions:

  • AlcoholAlcohol: According to secondary sources, some gentian preparations may contain alcohol, and concurrent use may cause additive effects.

    • Gentian/Lab Interactions:

  • Blood sugar.Blood sugar: According to secondary sources, some gentian preparations may contain sugar and may interfere with blood sugar control.