Boxwood

Boxwood/Drug Interactions:

  • AntihypertensivesAntihypertensives: Based on animal and in vivo study, boxwood may slightly increase, then markedly decrease, blood pressure (13).
  • Antiretroviral agentsAntiretroviral agents: Unsubstantiated reports have noted that SPV-30 (extract of boxwood, Arkopharma, France) may increase CD4 and CD8 cell count, and reduce HIV viral load, however available clinical evidence is inconclusive (1; 2; 3; 4; 5; 6; 7; 8; 9; 10).
  • Cholinergic agonistsCholinergic agonists: Based on in vitro study, boxwood may have acetylcholinesterase inhibition and butyrylcholinesterase activity (14; 13).
  • SteroidsSteroids: According to laboratory assays, boxwood contains steroidal alkaloids (15; 16).

    • Boxwood/Herb/Supplement Interactions:

  • AntiviralsAntivirals: Unsubstantiated reports have noted that SPV-30 (extract of boxwood, Arkopharma, France) may increase CD4 and CD8 cell count, and reduce HIV viral load, however available clinical evidence is inconclusive (1; 2; 3; 4; 5; 6; 7; 8; 9; 10).
  • Cholinergic herbsCholinergic herbs: Based on in vitro study, boxwood may have acetylcholinesterase and butyrylcholinesterase inhibition activity (14; 13).
  • HypotensivesHypotensives: Based on animal and in vivo study, boxwood may slightly increase or markedly decrease blood pressure (13).
  • SteroidsSteroids: According to laboratory assays, boxwood contains steroidal alkaloids (15; 16).

    • Boxwood/Food Interactions:

  • Insufficient available evidence.

    • Boxwood/Lab Interactions:

  • CD4 countCD4 count: Unsubstantiated reports have noted that SPV-30 (extract of boxwood, Arkopharma, France) may increase CD4 and CD8 cell count, and reduce HIV viral load, however available clinical evidence is inconclusive (1; 2; 3; 4; 5; 6; 7; 8; 9; 10).
  • CD8 countCD8 count: Unsubstantiated reports have noted that SPV-30 (extract of boxwood, Arkopharma, France) may increase CD4 and CD8 cell count, and reduce HIV viral load, however available clinical evidence is inconclusive (1; 2; 3; 4; 5; 6; 7; 8; 9; 10).
  • HIV viral countsHIV viral counts: Unsubstantiated reports have noted that SPV-30 (extract of boxwood, Arkopharma, France) may increase CD4 and CD8 cell count, and reduce HIV viral load, however available clinical evidence is inconclusive (1; 2; 3; 4; 5; 6; 7; 8; 9; 10).