Broccoli sprout extract

Broccoli sprout/Drug Interactions:

  • AntihypertensivesAntihypertensives: In spontaneously hypertensive stroke-prone rats, dried broccoli sprouts (containing glucoraphanin) reduced blood pressure (34).
  • AntilipemicsAntilipemics: In healthy humans that consumed fresh broccoli sprouts, total cholesterol and LDL cholesterol levels decreased, and HDL cholesterol levels significantly increased (35).
  • Cytochrome P450metabolized agentsCytochrome P450-metabolized agents: According to a review, sulforaphane has been observed to inhibit CYP3A4, an isozyme commonly involved in drug-drug interactions (36).
  • Ultraviolet protective agents (UV protection)Ultraviolet protective agents (UV protection): In humans, topical application of sulforaphane-rich broccoli sprout extracts significantly reduced susceptibility to erythema caused by ultraviolet (UV) radiation (40). In mice, oral or topical application of sulforaphane-rich broccoli sprout extracts protected against UV radiation-induced inflammation, edema, and skin carcinogenesis (40; 47; 48).

    • Broccoli sprout/Herb/Supplement Interactions:

  • AntilipemicsAntilipemics: In healthy humans that consumed fresh broccoli sprouts, total cholesterol and LDL cholesterol levels decreased, and HDL cholesterol levels significantly increased (35).
  • Cytochrome P450-metabolized herbs and supplementsCytochrome P450-metabolized herbs and supplements: According to a review, sulforaphane has been observed to inhibit CYP3A4, an isozyme commonly involved in drug-drug interactions (36).
  • HypotensivesHypotensives: In spontaneously hypertensive stroke-prone rats, dried broccoli sprouts (containing glucoraphanin) reduced blood pressure (34).
  • Radioprotective agentsRadioprotective agents: In humans, topical application of sulforaphane-rich broccoli sprout extracts significantly reduced susceptibility to erythema caused by ultraviolet (UV) radiation (40). In mice, oral or topical application of sulforaphane-rich broccoli sprout extracts protected against UV radiation-induced inflammation, edema, and skin carcinogenesis (40; 47; 48).

    • Broccoli sprout/Food Interactions:

  • Insufficient available evidence.

    • Broccoli sprout/Lab Interactions:

  • Blood pressureBlood pressure: In spontaneously hypertensive stroke-prone rats fed rats, dried broccoli sprouts (containing glucoraphanin) significantly lowered blood pressure (34).
  • Cholesterol levelsCholesterol levels: In healthy humans that consumed fresh broccoli sprouts, total cholesterol and LDL cholesterol levels decreased, and HDL cholesterol levels significantly increased (35).