Garcinia mangostana

Mangosteen/Drug Interactions:

  • Anticoagulant agentsAnticoagulant agents: Based on in vitro studies, mangosteen may have an anticoagulant effect (8; 9; 12).
  • Anti-histamine agentsAnti-histamine agents: Based on in vitro studies, mangosteen may have an anti-histamine effect (9; 1).
  • Chemotherapeutic agentsChemotherapeutic agents: Due to anti-oxidant effects, mangosteen may interaction with chemotherapeutic agents (i.e., anthracyclines, platinum compounds, and alkylating agents) whose mechanism of action involves oxidation (13).
  • Phosphodiesterase inhibitorsPhosphodiesterase inhibitors: Based on laboratory study, mangosteen may inhibit phosphodiesterase (14).
  • Selective serotonin reuptake inhibitor (SSRI) antidepressant agentsSelective serotonin reuptake inhibitor (SSRI) antidepressant agents: Based on in vitro studies, mangosteen may block serotonin receptors (9).

    • Mangosteen/Herb/Supplement Interactions:

  • Anticoagulant agentsAnticoagulant agents: Based on in vitro studies, mangosteen may have an anticoagulant effect (8; 9; 12).

    • Mangosteen/Food Interactions:

  • Insufficient available evidence.

    • Mangosteen/Lab Interactions:

  • Coagulation panelCoagulation panel: Based on in vitro studies, mangosteen may have an anticoagulant effect (8; 9).
  • Histamine levelsHistamine levels: Based on in vitro studies, mangosteen may block histamine receptors (9; 1).
  • Phosphodiesterase levelsPhosphodiesterase levels: Based on laboratory study, mangosteen may inhibit phosphodiesterase (14).
  • Serotonin levelsSerotonin levels: Based on in vitro studies, mangosteen may block serotonin receptors (9).