Hamamelis virginiana

Witch hazel/Drug Interactions:

  • Anti-diabetic agentsAnti-diabetic agents: In vitro, witch hazel demonstrated insulin-stimulating and hypoglycemic effects (19).
  • AntibioticsAntibiotics: In vitro, witch hazel has shown activity against Staphylococcus aureus and many aerobic species commonly associated with periodontal disease (18; 13; 20).
  • AntifungalsAntifungals: In vitro, witch hazel has shown activity against Candida albicans (18; 13; 20).
  • Antiinflammatory agentsAntiinflammatory agents: Results of clinical studies indicate that topical application of witch hazel may have antiinflammatory effects (10; 1; 3).
  • AntiviralsAntivirals: In vitro, witch hazel has shown activity against Herpes simplex-l (18; 13; 20).
  • Antiulcer agentsAntiulcer agents: In vitro, proanthocyanidin fractions isolated from extracts of witch hazel bark exhibited cytoprotective effects in human cells (6).

    • Witch hazel/Herb/Supplement Interactions:

  • AntibacterialsAntibacterials: In vitro, witch hazel has shown activity against Staphylococcus aureus and many aerobic species commonly associated with periodontal disease (18; 13; 20).
  • AntifungalsAntifungals: In vitro, witch hazel has shown activity against Candida albicans (18; 13; 20).
  • Antiinflammatory herbs and supplementsAntiinflammatory herbs and supplements: Results of clinical studies indicate that topical application of witch hazel may have antiinflammatory effects (10; 1; 3).
  • AntioxidantsAntioxidants: Hamamelitannin and proanthocyanidins isolated from witch hazel bark demonstrated potent antioxidant activity in vitro (5; 7; 8; 27).
  • Antiulcer herbs and supplementsAntiulcer herbs and supplements: In vitro, proanthocyanidin fractions isolated from extracts of witch hazel bark exhibited cytoprotective effects in human cells (6).
  • AntiviralsAntivirals: In vitro, witch hazel has shown activity against Herpes simplex-l (18; 13; 20).
  • HypoglycemicsHypoglycemics: In vitro, witch hazel demonstrated insulin-stimulating and hypoglycemic effects (19).
  • Tannin containing herbs and supplementsTannin containing herbs and supplements: Tannins have been isolated from the leaves, bark, and stems of witch hazel (28; 29; 14; 30).

    • Witch hazel/Food Interactions:

  • Tannin containing foodsTannin containing foods: Tannins have been isolated from the leaves, bark, and stems of witch hazel (31; 29; 14; 30).

    • Witch hazel/Lab Interactions:

  • Glucose levelsGlucose levels: In vitro, witch hazel demonstrated insulin-stimulating and hypoglycemic effects (19).