Hydrangea

Hydrangea/Drug Interactions:

  • Antidiabetic agentsAntidiabetic agents: Hydrangenol, processed from the leaves of Hydrangea macrophylla var. thunbergii, have significantly lowered blood glucose levels in mice (2).
  • AntifungalsAntifungals: An ethylene-induced, chitin-binding protein (designated as HM30) from leaves of Hydrangea macrophylla was found to have antifungal activity toward several crop fungal pathogens (1).
  • AntihistaminesAntihistamines: Secondary sources report that hydrangeol, a synthetic derivative of hydrangea, possesses anti-allergic properties, possibly via the inhibition of hyaluronidase activity and histamine release. According to laboratory study, thunberginol constituents from hydrangea may have anti-allergic effects (13).
  • Antilipemic agentsAntilipemic agents: Hydrangenol, processed from the leaves of Hydrangea macrophylla var. thunbergii, significantly lowered free fatty acid levels in mice (2).
  • Antimalarial agentsAntimalarial agents: Some alkaloid containing fractions prepared from the leaves of Hydrangea macrophylla Seringe var. Otaksa Makino have increased survival in malaria infected mice (3).
  • Hair loss prevention agentsHair loss prevention agents: In in vitro and animal study, researchers have demonstrated that an extract of Hydrangea macrophylla may be effective in preventing male pattern baldness (4).

    • Hydrangea/Herb/Supplement Interactions:

  • AntifungalsAntifungals: An ethylene induced, chitin-binding protein (designated as HM30) from the leaves of Hydrangea macrophylla was found to have antifungal activity toward several crop fungal pathogens (1).
  • AntihistaminesAntihistamines: Secondary sources report that hydrangeol, a synthetic derivative of hydrangea, possesses anti-allergic properties, possibly via the inhibition of hyaluronidase activity and histamine release. According to laboratory study, thunberginol constituents from hydrangea may have anti-allergic effects (13).
  • AntilipemicsAntilipemics: Hydrangenol, processed from the leaves of Hydrangea macrophylla var. thunbergii, significantly lowered free fatty acid levels in mice (2).
  • Antimalarial herbs and supplementsAntimalarial herbs and supplements: Some alkaloid containing fractions prepared from the leaves of Hydrangea macrophylla Seringe var. Otaksa Makino have increased survival in malaria infected mice (3).
  • Hair loss prevention agentsHair loss prevention agents: In in vitro and animal study, researchers have demonstrated that an extract of Hydrangea macrophylla may be effective in preventing male pattern baldness (4).
  • HypoglycemicsHypoglycemics: Hydrangenol, processed from the leaves of Hydrangea macrophylla var. thunbergii, significantly lowered blood glucose levels in mice (2).

    • Hydrangea/Food Interactions:

  • Insufficient available evidence.

    • Hydrangea/Lab Interactions:

  • Blood glucose levelsBlood glucose levels: Hydrangenol processed from the leaves of Hydrangea macrophylla var. thunbergii, significantly lowered blood glucose levels in mice (2).
  • Free fatty acid levelsFree fatty acid levels: Hydrangenol, processed from the leaves of Hydrangea macrophylla var. thunbergii, significantly lowered free fatty acid levels in mice (2).