Jamaican dogwood
Jamaican dogwood/Drug Interactions:
AcaricidalsAcaricidals: In vitro, the acaricidal effects of Piscidia piscipula and other plants high in tannins were shown against cattle ticks (1). The LC50 value of P. piscipula extract was 2.466mcg/mL. AnalgesicsAnalgesics: According to secondary sources, Jamaican dogwood may decrease pelvic pain by increasing blood flow to the area and may decrease general pain by inhibiting enzymes involved in inflammation.AnestheticsAnesthetics: According to secondary sources, Jamaican dogwood should be discontinued at least two weeks prior to surgery, due to potential interactions with anesthetics.Antianxiety agentsAntianxiety agents: According to a review, Piscidia erythrina had sedative or anxiolytic effects, and a combination of extracts of Crataegus oxyacantha, Valeriana officinalis, Passiflora incarnata, Matricaria chamomilla, Piscidia erythrina, and Hyoscyamus niger had sedative effects at a high dose and anxiolytic effects at a low dose (13). Further details are lacking at this time. AntidermatophytesAntidermatophytes: In vitro, Piscidia piscipula had antidermatophyte effects (3). AntihypertensivesAntihypertensives: According to secondary sources, Jamaican dogwood increases blood pressure (12). Further details are lacking.AntispasmodicsAntispasmodics: The spasmolytic effects of isoflavones from Piscidia erythrina have been discussed (8). Yarnell et al. published a review on botanicals, such as Piscidia piscipula, with spasmolytic effects (7). According to secondary sources, Jamaican dogwood decreased the amplitude of contractions of excised rabbit intestine and guinea pig uterus (12). Further details on these reports are lacking at this time. Cardiovascular agentsCardiovascular agents: According to secondary sources, Jamaican dogwood increases blood pressure (12). According to secondary sources, toxic doses of Jamaican dogwood decrease the action of the heart, first increase and then decrease arterial tension, and decrease pulse rate.Central nervous system agentsCentral nervous system agents: According to a review, Piscidia erythrina had sedative or anxiolytic effects, and a combination of extracts of Crataegus oxyacantha, Valeriana officinalis, Passiflora incarnata, Matricaria chamomilla, Piscidia erythrina, and Hyoscyamus niger had sedative effects at a high dose and anxiolytic effects at a low dose (13). Further details are lacking at this time. According to secondary sources, Jamaican dogwood may cause drowsiness and lack of coordination, and may reduce reflex action, including tetanic spasm. According to limited data, during chemical and physiological methods of standardization of Jamaican dogwood, incoordination and ataxia were reported (12). According to secondary sources, symptoms of Jamaican dogwood overdose include numbness, tremors, salivation, and sweating. According to secondary sources, toxic doses of Jamaican dogwood may eliminate sensation and cause diminished reflexes, general paralysis, convulsions, and death. Gastrointestinal agentsGastrointestinal agents: According to secondary sources, Jamaican dogwood may cause gastric distress and nausea.Ophthalmic agentsOphthalmic agents: According to secondary sources, Jamaican dogwood may cause dilation of the pupils.Respiratory agentsRespiratory agents: According to secondary sources, Jamaican dogwood may cause dyspnea and respiratory paralysis.SedativesSedatives: According to a review, Piscidia erythrina had sedative or anxiolytic effects, and a combination of extracts of Crataegus oxyacantha, Valeriana officinalis, Passiflora incarnata, Matricaria chamomilla, Piscidia erythrina, and Hyoscyamus niger had sedative effects at a high dose and anxiolytic effects at a low dose (13). Further details are lacking at this time. Skeletal muscle relaxantsSkeletal muscle relaxants: According to secondary sources, Jamaican dogwood may cause muscular relaxation and lack of coordination.Jamaican dogwood/Herb/Supplement Interactions:
AcaricidalsAcaricidals: In vitro, the acaricidal effects of Piscidia piscipula and other plants high in tannins were shown against cattle ticks (1). The LC50 value of P. piscipula extract was 2.466mcg/mL. AnalgesicsAnalgesics: According to secondary sources, Jamaican dogwood may decrease pelvic pain by increasing blood flow to the area and may decrease general pain by inhibiting enzymes involved in inflammation.AnestheticsAnesthetics: According to secondary sources, Jamaican dogwood should be discontinued at least two weeks prior to surgery, due to potential interactions with anesthetics.Antianxiety agentsAntianxiety agents: According to a review, Piscidia erythrina had sedative or anxiolytic effects, and a combination of extracts of Crataegus oxyacantha, Valeriana officinalis, Passiflora incarnata, Matricaria chamomilla, Piscidia erythrina, and Hyoscyamus niger had sedative effects at a high dose and anxiolytic effects at a low dose (13). Further details are lacking at this time. AntidermatophytesAntidermatophytes: In vitro, Piscidia piscipula had antidermatophyte effects (3). AntispasmodicsAntispasmodics: The spasmolytic effects of isoflavones from Piscidia erythrina have been discussed (8). Yarnell et al. published a review on botanicals, such as Piscidia piscipula, with spasmolytic effects (7). According to secondary sources, Jamaican dogwood decreased the amplitude of contractions of excised rabbit intestine and guinea pig uterus (12). Further details on these reports are lacking at this time. Black hawBlack haw: According to secondary sources, for painful periods, Jamaican dogwood has been taken with black haw or cramp bark (14).Cardiovascular agentsCardiovascular agents: According to secondary sources, Jamaican dogwood increases blood pressure (12). According to secondary sources, toxic doses of Jamaican dogwood decrease action of the heart, first increase and then decrease arterial tension, and decrease pulse rate.Central nervous system agentsCentral nervous system agents: According to a review, Piscidia erythrina had sedative or anxiolytic effects, and a combination of extracts of Crataegus oxyacantha, Valeriana officinalis, Passiflora incarnata, Matricaria chamomilla, Piscidia erythrina, and Hyoscyamus niger had sedative effects at a high dose and anxiolytic effects at a low dose (13). Further details are lacking at this time. According to secondary sources, Jamaican dogwood may cause drowsiness and lack of coordination and may reduce reflex action, including tetanic spasm. According to limited data, during chemical and physiological methods of standardization of Jamaican dogwood, incoordination and ataxia were reported (12). According to secondary sources, symptoms of Jamaican dogwood overdose include numbness, tremors, salivation, and sweating. According to secondary sources, toxic doses of Jamaican dogwood may eliminate sensation and cause diminished reflexes, general paralysis, convulsions, and death. Cramp barkCramp bark: According to secondary sources, for painful periods, Jamaican dogwood has been taken with black haw or cramp bark (14).Gastrointestinal agentsGastrointestinal agents: According to secondary sources, Jamaican dogwood may cause gastric distress and nausea.HopsHops: According to secondary sources, for easing of insomnia, Jamaican dogwood has been taken with hops, passionflower, or valerian.Hypertensives and hypotensivesHypertensives and hypotensives: According to secondary sources, Jamaican dogwood increases blood pressure (12).MineralsMinerals: According to secondary sources, the isoflavone constituents of Jamaican dogwood may increase absorption of vitamins and minerals and prevent vitamin C from being oxidized.Musculoskeletal agentsMusculoskeletal agents: According to secondary sources, Jamaican dogwood may cause muscular relaxation and lack of coordination.Ophthalmic agentsOphthalmic agents: According to secondary sources, Jamaican dogwood may cause dilation of the pupils.PassionflowerPassionflower: According to secondary sources, for easing of insomnia, Jamaican dogwood has been taken with hops, passionflower, or valerian.Respiratory agentsRespiratory agents: According to secondary sources, Jamaican dogwood may cause dyspnea and respiratory paralysis.SedativesSedatives: According to a review, Piscidia erythrina had sedative or anxiolytic effects, and a combination of extracts of Crataegus oxyacantha, Valeriana officinalis, Passiflora incarnata, Matricaria chamomilla, Piscidia erythrina, and Hyoscyamus niger had sedative effects at a high dose and anxiolytic effects at a low dose (13). Further details are lacking at this time. ValerianValerian: According to secondary sources, for easing of insomnia, Jamaican dogwood has been taken with hops, passionflower, or valerian.VitaminsVitamins: According to secondary sources, isoflavone constituents of Jamaican dogwood may increase absorption of vitamins and minerals and prevent vitamin C from being oxidized.Jamaican dogwood/Food Interactions:
GeneralGeneral: According to secondary sources, isoflavone constituents of Jamaican dogwood may increase absorption of vitamins and minerals from food.Jamaican dogwood/Lab Interactions:
Blood pressureBlood pressure: According to secondary sources, Jamaican dogwood increases blood pressure (12).PulsePulse: According to secondary sources, toxic doses of Jamaican dogwood decrease the action of the heart, first increase and then decrease arterial tension, and decrease pulse rate.