Justicia pectoralis

Justicia pectoralis/Drug Interactions:

  • AnalgesicsAnalgesics: In animal research, hydroalcoholic extracts (HAEs) from Justicia pectoralis had antinociceptive effects (6).
  • Antianxiety agentsAntianxiety agents: In animal research, Justicia pectoralis exerted anxiolytic effects and lacked sedative effects (5).
  • AntibioticsAntibiotics: In vitro,Justicia pectoralis inhibited growth of Escherichia coli and Staphylococcus epidermidis and partially inhibited Enterococcus faecalis (4).
  • AnticoagulantsAnticoagulants: Theoretically, the coumarin in Justicia pectoralis may be transformed into dicoumarol, a natural anticoagulant.
  • Anti-inflammatoriesAnti-inflammatories: In vitro, Justicia pectoralis inhibited COX-2 catalytic activity (3).
  • AntineoplasticsAntineoplastics: In vitro, the cytotoxic principle 1-aryl-2,3-naphthalide lignan (justicidin B) was isolated in Justicia pectoralis extract (11).
  • AntipsychoticsAntipsychotics: Traditionally, Justicia pectoralis has been used as a hallucinogenic snuff ingredient.
  • CNS depressantsCNS depressants: Evidence from animal research suggests that Justicia pectoralis may elicit an almost complete inhibition of traction performance due to muscular relaxant activity that decreases muscle tone (1).
  • ContraceptivesContraceptives: Traditionally, Justicia pectoralis has been used for treatment of menopause and premenstrual syndrome (PMS). In vitro, Justicia pectoralis exerted estrogenic and progestogenic effects (3).
  • Fertility agentsFertility agents: Traditionally, Justicia pectoralis has been used for treatment of menopause and premenstrual syndrome (PMS). In vitro, Justicia pectoralis exerted estrogenic and progestogenic effects (3).
  • Hormonal agentsHormonal agents: Traditionally, Justicia pectoralis has been used for treatment of menopause and premenstrual syndrome (PMS). In vitro, Justicia pectoralis exerted estrogenic and progestogenic effects (3).
  • Muscle relaxantsMuscle relaxants: Evidence from animal research suggests that Justicia pectoralis may have muscular relaxant activity that decreases muscle tone (1).
  • Neurologic agentsNeurologic agents: Animal research suggests that Justicia pectoralis may elicit an almost complete inhibition of traction performance due to muscular relaxant activity that decreases muscle tone (1). Justicia pectoralis has been traditionally used as a hallucinogenic snuff ingredient. Western hemisphere Indians have used Justicia pectoralis as an intoxicating snuff during rituals (8). However, in vitro and animal research lacks confirmation of alkaloid content sufficient enough to cause significant gross behavioral effects, suggesting evidence against a possible hallucinogenic effect (8).
  • Pulmonary agentsPulmonary agents: In animal research, hydroalcoholic extracts (HAEs) from Justicia pectoralis caused bronchodilator effects (6).

    • Justicia pectoralis/Herb/Supplement Interactions:

  • AnalgesicsAnalgesics: In animal research, hydroalcoholic extracts (HAEs) from Justicia pectoralis had antinociceptive effects (6).
  • Antianxiety agentsAntianxiety agents: In animal research, Justicia pectoralis exerted anxiolytic effects and lacked sedative effects (5).
  • AntibacterialsAntibacterials: In vitro,Justicia pectoralis inhibited growth of Escherichia coli and Staphylococcus epidermidis and partially inhibited Enterococcus faecalis (4).
  • AnticoagulantsAnticoagulants: Theoretically, the coumarin in Justicia pectoralis may be transformed into dicoumarol, a natural anticoagulant.
  • Anti-inflammatoriesAnti-inflammatories: In vitro, Justicia pectoralis inhibited COX-2 catalytic activity (3).
  • AntineoplasticsAntineoplastics: In vitro, the cytotoxic principle 1-aryl-2,3-naphthalide lignan (justicidin B) was isolated in Justicia pectoralis extract (11).
  • AntipsychoticsAntipsychotics: Traditionally, Justicia pectoralis has been used as a hallucinogenic snuff ingredient.
  • CNS depressantsCNS depressants: Evidence from animal research suggests that Justicia pectoralis may elicit an almost complete inhibition of traction performance due to muscular relaxant activity that decreases muscle tone (1).
  • ContraceptivesContraceptives: Traditionally, Justicia pectoralis has been used for treatment of menopause and premenstrual syndrome (PMS). In vitro, Justicia pectoralis exerted estrogenic and progestogenic effects (3).
  • Fertility agentsFertility agents: Traditionally, Justicia pectoralis has been used for treatment of menopause and premenstrual syndrome (PMS). In vitro, Justicia pectoralis exerted estrogenic and progestogenic effects (3).
  • Hormonal herbs and supplementsHormonal herbs and supplements: Traditionally, Justicia pectoralis has been used for treatment of menopause and premenstrual syndrome (PMS). In vitro, Justicia pectoralis exerted estrogenic and progestogenic effects (3).
  • Muscle relaxantsMuscle relaxants: Evidence from animal research suggests that Justicia pectoralis may have muscular relaxant activity that decreases muscle tone (1).
  • Neurologic agentsNeurologic agents: Animal research suggests that Justicia pectoralis may elicit an almost complete inhibition of traction performance due to muscular relaxant activity that decreases muscle tone (1). Justicia pectoralis has been traditionally used as a hallucinogenic snuff ingredient. Western hemisphere Indians have used Justicia pectoralis as an intoxicating snuff during rituals (8). However, in vitro and animal research lacks confirmation of alkaloid content sufficient enough to cause significant gross behavioral effects, suggesting evidence against a possible hallucinogenic effect (8).
  • Pulmonary agentsPulmonary agents: In animal research, hydroalcoholic extracts (HAEs) from Justicia pectoralis caused bronchodilator effects (6).

    • Justicia pectoralis/Food Interactions:

  • Insufficient available evidence.

    • Justicia pectoralis/Lab Interactions:

  • Coagulation panelCoagulation panel: Theoretically, the coumarin in Justicia pectoralis may be transformed into dicoumarol, a natural anticoagulant.