Liver extract

Liver extract/Drug Interactions:

  • AntacidsAntacids: Based on a clinical study, liver extract added to the duodenum or antral jejunum may increase gastric acid and pepsin outputs (13; 11). However, liver extract added to the proximal jejunum did not affect gastric acid or pepsin output (11).
  • Anticoagulants/antiplatelet drugsAnticoagulants/antiplatelet drugs: Based on clinical study, liver extract may affect blood clotting (15; 6).
  • Antihypercholesterolemia drugsAntihypercholesterolemia drugs: Based on a clinical study, liver extract may improve plasma cholesterol levels in patients with impaired hepatic function (15).
  • AntioxidantsAntioxidants: Liver extract may be a rich source of the antioxidant superoxide dismutase (SOD).
  • Antiviral drugsAntiviral drugs: Based on animal and in vitro studies, liver extract in combination with interferon-alpha-2a may synergistically inhibit herpes simplex virus type-1 and influenza virus type A (4).
  • Cancer drugsCancer drugs: Based on in vitro studies, liver extract may reversibly inhibit thymidine and uridine incorporation into DNA and RNA during cell growth (19; 20) and dose-dependently catalyze the removal of O6-methylguanine (21).
  • Human growth hormoneHuman growth hormone: Based on a clinical study, liver extract may tend to normalize the metabolic clearance rate of human growth hormone in hepatopathic patients (23).
  • Immunomodulating drugsImmunomodulating drugs: Based on in vitro study, liver extract inhibits lymphocyte proliferation (22).
  • InterferonInterferon: Based on clinical studies, liver extract may increase the antiviral activity of interferon (4; 5).
  • IronIron: Liver extract may have a high content of heme iron (3-4mg/g).

    • Liver extract/Herb/Supplement Interactions:

  • AntacidsAntacids: Based on clinical studies, liver extract added to the duodenum or antral jejunum may increase gastric acid and pepsin outputs (13; 11). However, liver extract added to the proximal jejunum did not affect gastric acid or pepsin output (11).
  • Anticoagulants/antiplatelet herbsAnticoagulants/antiplatelet herbs: Based on clinical studies, liver extract may affect blood clotting (15; 6).
  • Antihypercholesterolemia herbsAntihypercholesterolemia herbs: Based on a clinical study, liver extract may improve plasma cholesterol levels in patients with impaired hepatic function (15).
  • AntioxidantsAntioxidants: Liver extract may be a rich source of the antioxidant superoxide dismutase (SOD).
  • Antiviral herbsAntiviral herbs: Based on animal and in vitro studies, liver extract in combination with interferon-alpha-2a may synergistically inhibit herpes simplex virus type-1 and influenza virus type A (4).
  • Cancer herbsCancer herbs: Based on in vitro studies, liver extract may reversibly inhibit thymidine and uridine incorporation into DNA and RNA during cell growth (19; 20) and dose-dependently catalyze the removal of O6-methylguanine (21).
  • Human growth hormoneHuman growth hormone: Based on a clinical study, liver extract may tend to normalize the metabolic clearance rate of human growth hormone in hepatopathic patients (23).
  • Immunomodulating herbsImmunomodulating herbs: Based on in vitro studystudies, liver extract inhibits lymphocyte proliferation (22).
  • InterferonInterferon: Based on clinical studies, liver extract may increase the antiviral activity of interferon (4; 5).
  • IronIron: Liver extract may a high content of heme iron (3-4mg/g).
  • Vitamin B12Vitamin B12: Based on a clinical study, liver extract, uridine diphosphate glucose, and vitamin B12 may have a hepatoprotective effect in patients with liver diseases (27). Based on another clinical study, liver extract and vitamin B12 may have a therapeutic effect in patients with liver diseases and rheumatoid arthritis (14).

    • Liver extract/Food Interactions:

  • Iron-containing foodsIron-containing foods: Liver extract has a high content of heme iron (3-4mg/g).

    • Liver extract/Lab Interactions:

  • CholesterolCholesterol: Based on a clinical study, liver extract may improve plasma cholesterol levels in patients with impaired hepatic function (15).
  • Coagulation timeCoagulation time: Based on clinical studies, liver extract may affect blood clotting (15; 6).
  • HemoglobinHemoglobin: Based on a clinical study, liver extract may improve hemoglobin concentration in patients with impaired hepatic function (15).
  • IronIron: Liver extract may increase iron concentrations and test results due to its iron content.
  • LymphocytesLymphocytes: Based on in vitro study, liver extract may inhibit lymphocyte proliferation (22).
  • ProteinProtein: Based on in vitro study, liver extract may inhibit protein production (22).
  • Red blood cell countRed blood cell count: Based on a clinical study, liver extract may improve red blood cell counts in patients with impaired hepatic function (15).