Luffa

Luffa operculata/Drug Interactions:

  • Antineoplastic agentsAntineoplastic agents: In in vitro research, neocucurbitacins A and B, constituents of Luffa operculata, inhibited polyomavirus-enhancer binding protein 2alphaA (PEBP2alphaA) and the gene expression of osteoclastogenesis-inhibitory factor (OCIF) in human osteoblast-like cells (9).
  • BisphosphonatesBisphosphonates: In in vitro research, neocucurbitacins A and B, constituents of Luffa operculata, inhibited polyomavirus enhancer-binding protein 2alphaA (PEBP2alphaA) and the gene expression of osteoclastogenesis-inhibitory factor (OCIF) in human osteoblast-like cells (9).
  • Intranasal agentsIntranasal agents: Disruption of epithelial tight junctions by Luffa operculata (6; 1) suggests that prior exposure to Luffa operculata may enhance the delivery of topical drugs in the same area.
  • Respiratory agentsRespiratory agents: In clinical research, the HEEL? combination product Sinusin? (containing Luffa operculata) performed as well as conventional cromolyn sodium therapy (5). Luffa operculata in combination with Lobaria pulmonaria and potassium dichromate increased secretolysis and decreased sinusitis symptoms in an open-label, practice-based study among 119 patients (4).

    • Luffa operculata/Herb/SupplementInteractions:

  • AntineoplasticsAntineoplastics: In in vitro research, neocucurbitacins A and B, constituents of Luffa operculata, inhibited polyomavirus enhancer-binding protein 2alphaA (PEBP2alphaA) and the gene expression of osteoclastogenesis-inhibitory factor (OCIF) in human osteoblast-like cells (9).
  • Intranasal herbs and supplementsIntranasal herbs and supplements: In vitro, disruption of epithelial tight junctions by Luffa operculata (6; 1) suggests that prior exposure to Luffa operculata may enhance the delivery of topical herbs in the same area.
  • Respiratory agentsRespiratory agents: In clinical research, the HEEL? combination product Sinusin? (containing Luffa operculata) performed as well as conventional cromolyn sodium therapy (5). Luffa operculata in combination with Lobaria pulmonaria and potassium dichromate increased secretolysis and decreased sinusitis symptoms in an open-label, practice-based study among 119 patients (4).

    • Luffa operculata/Food Interactions:

  • Insufficient available evidence.

    • Luffa operculata/Lab Interactions:

  • Insufficient available evidence.