Sulfur

Sulfur/Drug Interactions:

  • AnticoagulantsAnticoagulants: Sulfur water taken orally by patients with arteriosclerosis decreased platelet aggregability evoked by ADP and collagen, decreased spontaneous platelet aggregability, and increased fibrinolytic activity of the blood (elongation of euglobulin clot lysis time) (25).
  • Anti-inflammatoriesAnti-inflammatories: Sulfur inhalation therapy caused anti-inflammatory effects in children (47).
  • AntilipemicsAntilipemics: In two human studies, there was a statistically significant decrease of blood levels of total cholesterol, HDL cholesterol, and triglycerides following either drinking or soaking in sulfur water (25; 10). LDL cholesterol only decreased significantly in one study; the concentration of HDL cholesterol did not change significantly in either study.
  • IsotretinoinIsotretinoin: According to anecdotal reports, concurrent use of isotretinoin with sulfur products may synergistically increase skin irritation.
  • LaxativesLaxatives: Ingestion of sulfur has been reported to be mildly laxative, perhaps by the action of alkali sulfides, which are formed from sulfur in the small intestine (31).
  • RetinoidsRetinoids: According to anecdotal reports, concurrent use of retinoids with sulfur products may result in excessive irritation and/or drying.

    • Sulfur/Herb/Supplement Interactions:

  • AnticoagulantsAnticoagulants: Sulfur water taken orally by patients with arteriosclerosis decreased platelet aggregability evoked by ADP and collagen, decreased spontaneous platelet aggregability, and increased fibrinolytic activity of the blood (elongation of euglobulin clot lysis time) (25).
  • Anti-inflammatoriesAnti-inflammatories: Sulfur inhalation therapy caused anti-inflammatory effects in children (47).
  • AntilipemicsAntilipemics: In two human studies, there was a statistically significant decrease of blood levels of total cholesterol, HDL cholesterol, and triglycerides following either drinking or soaking in sulfur water (25; 10). LDL cholesterol only decreased significantly in one study; the concentration of HDL cholesterol did not change significantly in either study.
  • LaxativesLaxatives: Ingestion of sulfur has been reported to be mildly laxative, perhaps by the action of alkali sulfides, which are formed from sulfur in the small intestine (31).

    • Sulfur/Food Interactions:

  • Insufficient available evidence.

    • Sulfur/Lab Interactions:

  • ClottingClotting: Sulfur water taken orally by patients with arteriosclerosis decreased platelet aggregability evoked by ADP and collagen, decreased spontaneous platelet aggregability, and increased fibrinolytic activity of the blood (elongation of euglobulin clot lysis time) (25).
  • Lipid panelLipid panel: In two human studies, there was a statistically significant decrease of blood levels of total cholesterol, HDL cholesterol, and triglycerides following either drinking or soaking in sulfur water (25; 10). LDL cholesterol only decreased significantly in one study; the concentration of HDL cholesterol did not change significantly in either study.