Usnea

Usnea/Drug Interactions:

  • AntiplateletanticoagulantsAntiplatelet/anticoagulants: Based on in vitro study, usnea may increase bleeding time by inhibition of platelet aggregation (29).
  • Cytochrome P450 metabolizing agentsCytochrome P450 metabolizing agents: Based on animal and in vitro data, usnea may induce the cytochrome P450 system (58; 16).

    • Usnea/Herb/Supplement Interactions:

  • Antiplatelet/anticoagulantsAntiplatelet/anticoagulants: Based on in vitro study, usnea may increase bleeding time by inhibition of platelet aggregation (29).
  • Cytochrome P450 metabolizing agentsCytochrome P450 metabolizing agents: Based on animal and in vitro data, usnea may induce the cytochrome P450 system (58; 16).

    • Usnea/Food Interactions:

  • Insufficient available evidence.

    • Usnea/Lab Interactions:

  • Coagulation panelCoagulation panel: Based on in vitro study, usnea may alter antiplatelet activity potentially affecting prothrombin time (PT) (29).
  • Hepatic enzymesHepatic enzymes: Based on in vitro studies and human case reports of hepatotoxicity, usnic acid may alter the levels of hepatic enzymes (12; 50; 13; 14; 16).