Acemannan

Aloe/Nutrient Depletion:

  • GlucoseGlucose: Concomitant use of glucose-lowering agents with oral forms of aloe may increase hypoglycemic effects, according to preliminary human data (41; 40). In human research, compared to the placebo group following treatment, participants administered Aloe vera showed reduced mean glucose level (+5.2 ? 25.1% vs. -4.8 ? 14.7% change) (45).
  • LipidsLipids: Compared to baseline, participants receiving Aloe vera showed decreased levels of total cholesterol (15.4-15.5%), low-density lipoprotein (LDL) cholesterol (18.2-18.9%), and triglycerides (25.2-31.9%). Information regarding between-group differences was lacking (46). In human research, aloe has demonstrated further antilipemic effects (45; 64).
  • PotassiumPotassium: Based on the laxative properties of oral aloe latex, prolonged use may cause potassium depletion, metabolic alkalosis, and dehydration.
  • Vitamin CVitamin C: According to human research, aloe may slow the absorption of vitamin C (129).
  • Vitamin EVitamin E: According to human research, aloe may slow the absorption of vitamin E (129).