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Black seed
Black seed/Nutrient Depletion:
Blood glucose
Blood glucose: Based on human study (
124
) and animal diabetic models, improved glucose tolerance and reduced blood glucose has been shown in animal diabetic models (
115
;
48
;
116
;
117
;
118
;
119
;
120
;
121
;
122
;
123
;
142
). Crushed seeds and oil lowered blood glucose in human study (273).
Lipids
Lipids: Based on human study, black seed oil was shown to modulate lipid levels (
5
;
124
). Based on animal study, Nigella sativa or thymoquinone has been shown to protect against induced increases in or to reduce cholesterol levels (
66
;
125
;
126
;
127
;
74
;
128
;
129
;
142
;
278
; 130).
Minerals
Minerals: Based on animal study, Nigella sativa seed extract increased diuresis and urinary excretion of Cl, Na, and K (
50
). Based on animal study, Nigella sativa injection decreased elevated serum K and Ca levels (
274
).
Protein
Protein: Based on animal study, Nigella sativa suppressed doxorubicin-induced proteinuria and albuminuria (
74
).