Lignans

Lignan/Nutrient Depletion:

  • CholesterolCholesterol: In human and animal research, lignans like sesamin treatment significantly reduced total cholesterol, LDL cholesterol, and apoprotein B (110; 83; 109; 36).
  • GlucoseGlucose: In humans, treatment with CPH 82 (Reumacon?), a purified semisynthetic lignan glycoside derivative of the medicinal herb Podophyllum emodi, resulted in a decrease in serum glucose (84).
  • SodiumSodium: Based on a rat study, the lignan elenoside may have an antidiuretic effect and decrease sodium excretion (44).
  • Vitamin EVitamin E: Based on in vitro and clinical studies, ingestion of the lignan sesamin may significantly reduce the metabolism of vitamin E and decrease serum and urinary levels of its metabolites (167; 87).