Monacolin K

Red yeast rice/Nutrient Depletions:

  • Coenzyme Q10 (CoQ10)Coenzyme Q10 (CoQ10): In clinical research, three months of statin treatment lowered plasma and platelet levels of CoQ10 in the absence of CoQ10 supplementation (125). Serum CoQ10 decreased by up to 30% with use of statins, including lovastatin (126; 127; 128; 129).
  • Hemoglobin levelsHemoglobin levels: In animal research, red yeast rice decreased hemoglobin (22).
  • GlucoseGlucose: In animal and human clinical trials, RYR decreased glucose (62; 61; 60). However, another animal study noted increased glucose with RYR use (22).
  • LipidsLipids: In human clinical trials, RYR decreased TC, LDL-C, TG, Lp(a), and apo B, and/or increased HDL-C and apo A-1 (3; 6; 7; 8; 9; 10; 79; 34; 31; 44; 114; 45; 85; 35; 75; 73; 74; 36; 69; 115; 43; 33; 109; 82; 39; 49; 32; 77; 50; 51; 52; 80; 81). In human clinical trials, RYR in combination products lowered cholesterol levels (116; 103; 117; 108; 118; 107; 119; 120; 102).