N-Acetyl Cysteine

NAC/Nutrient depletions:

  • MagnesiumMagnesium: Magnesium deficiency has been associated with treatment with NAC and other antioxidants (47).
  • Urinary sodiumUrinary sodium: Significant increases in urinary sodium occurred with NAC supplementation in a case series (385).
  • ZincZinc: Concurrent ingestion of NAC and zinc favored gastrointestinal absorption of zinc (168). However, high doses of NAC (approximately 800mg) may induce zinc depletion by increasing the metal's urinary excretion (168).