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N-Acetyl Cysteine
NAC/Nutrient depletions:
Magnesium
Magnesium: Magnesium deficiency has been associated with treatment with NAC and other antioxidants (
47
).
Urinary sodium
Urinary sodium: Significant increases in urinary sodium occurred with NAC supplementation in a case series (
385
).
Zinc
Zinc: Concurrent ingestion of NAC and zinc favored gastrointestinal absorption of zinc (
168
). However, high doses of NAC (approximately 800mg) may induce zinc depletion by increasing the metal's urinary excretion (
168
).