Nicotinamide

Nicotinamide/Nutrient Depletion:

  • GlucoseGlucose: In clinical research, hypoglycemia has been reported (12).
  • LipidsLipids: In human research, nicotinamide reduced serum low-density lipoprotein (LDL) cholesterol concentrations in hemodialysis patients with hyperphosphatemia (9).
  • PhosphorusPhosphorus: In human research, nicotinamide decreased serum levels of phosphorus in hemodialysis patients with hyperphosphatemia (9). In animal research, nicotinamide increased kidney NAD levels, which inhibited phosphate reuptake in the proximal tubules (32)