OKG

Ornithine alpha-ketoglutarate (OKG)/Nutrient Depletion:

  • GlucoseGlucose: In human research, supplementation of OKG enterally (10; 19; 39) or intravenously (20) increased insulin secretion. Also, according to literature review, hypoglycemia was experienced by elderly patients being treated with OKG (21). However, according to commentary on this review, hypoglycemia was lacking in the mentioned study, but the effect has been observed in participants administered high doses (20g) of OKG (22).
  • PhenylalaninePhenylalanine: OKG supplementation has been shown to reduce phenylalanine concentrations (2).