Pancreatic enzymes

Pancreatin/Nutrient Depletions:

  • GlucoseGlucose: In patients with diabetes, changing treatment from pancreatin to placebo and vice versa resulted in major problems with glucose control (abnormal glucose control in 28 of 29 patients, one patient requiring hospitalization for symptomatic hypoglycemia, and one patient developing diabetic ketoacidosis) (26).
  • Folic acidFolic acid: In human study, pancreatic enzymes were associated with decreased absorption of folate (44).
  • IronIron: The effect of pancreatin on iron levels has been investigated (83). Based on secondary sources, pancreatic enzymes may be reduced by oral iron supplementation.