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Rebaudioside A
Stevia/Nutrient Depletion:
Electrolytes
Electrolytes: In animal research, high doses of stevia affected renal activity and perfusion, sodium excretion, and urinary flow (
30
;
31
;
32
).
Glucose
Glucose: Stevioside and aqueous extracts of Stevia rebaudiana leaves have been shown to decrease glucose levels in human (
5
;
29
) and animal (
5
;
29
) research. Rebaudioside A, a glycoside found in stevia, has been found to stimulate the production and activity of insulin (
2
).
Lipids
Lipids: Stevia rebaudiana Bertoni extract supplementation improved lipid and carnitine profiles in C57BL/6J mice fed a high-fat diet, as evidenced by decreased triglyceride concentrations in serum and liver (
52
).