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Resveratrol
Resveratrol/Nutrient Depletion:
Glucose
Glucose: Based on a proposed mechanism of action, resveratrol may have the potential to aid in insulin resistance syndrome and type 2 diabetes (
176
). In animal and human research, resveratrol has been shown to increase insulin sensitivity (
137
;
138
). In animal and human research, resveratrol reduced blood glucose (
139
;
135
;
136
;
138
). In epidemiological research, high urinary levels of resveratrol metabolites, a marker of wine and resveratrol intake, were associated with beneficial changes in fasting blood glucose (
141
).
Lipids
Lipids: In animal and human research, resveratrol, as well as LGP, which is rich in resveratrol, has been shown to reduce plasma triglycerides, LDL cholesterol, and apolipoprotein B and E concentrations, and to decrease cholesterol ester transfer protein activity (
185
;
82
;
136
;
135
;
157
). In epidemiological research, high urinary levels of resveratrol metabolites, a marker of wine and resveratrol intake, were associated with beneficial changes in blood lipids (HDL cholesterol, triglycerides) (
141
).
Protein
Protein: In human research, resveratrol decreased total protein (
136
).