Sage

Sage/Nutrient Depletion:

  • LipidsLipids: Sage lowered plasma LDL cholesterol and total cholesterol and elevated HDL cholesterol in healthy humans after two weeks of treatment (48; 116).
  • GlucoseGlucose: In vitro, sage had antidiabetic activity (25; 111). Also, in animal research, sage lowered plasma glucose, increased hepatocyte sensitivity to insulin, and inhibited gluconeogenesis in vitro, but lacked an effect on glucose clearance (108; 109; 110).