Cardo bendito
Related Terms
- Bitter thistle, Carbenia benedicta, cardin, Cardo Santo, Carduus benedictus, Chardon Benit, Cnici benedicti herba, cnicus, holy thistle, Kardo-benedictenkraut, St. Benedict thistle, salonitenolide, spotted thistle.
- Note: Blessed thistle should not be mistaken for milk thistle (Silybum marianus) or other members of the thistle family.
Background
- Blessed thistle leaves, stems, and flowers have traditionally been used in "bitter" tonic drinks and in other preparations taken by mouth to enhance appetite and digestion. Blessed thistle may also be included in the unproven anti-cancer herbal remedy Essiac?. This herb has been tested in laboratory studies for its properties against infections, cancer, and inflammation with promising results. However, high-quality trials showing benefits in humans are lacking.
Evidence Table
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. |
GRADE * |
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. |
GRADE * |
Laboratory studies report that blessed thistle (and chemicals in blessed thistle such as cnicin and polyacetylene) has activity against several types of bacteria and no effects on some types. Reliable human study is lacking. Further evidence is necessary in this area before a firm conclusion can be drawn.
|
C |
Laboratory studies report that blessed thistle (and chemicals in blessed thistle such as cnicin and polyacetylene) has activity against several types of bacteria and no effects on some types. Reliable human study is lacking. Further evidence is necessary in this area before a firm conclusion can be drawn.
|
C |
Blessed thistle is traditionally believed to stimulate stomach acid secretion and has been used as a treatment for indigestion or gas. However, there is limited scientific study in these areas. Additional research is needed before a firm conclusion can be reached.
|
C |
Blessed thistle is traditionally believed to stimulate stomach acid secretion and has been used as a treatment for indigestion or gas. However, there is limited scientific study in these areas. Additional research is needed before a firm conclusion can be reached.
|
C |
Laboratory studies report no activity of blessed thistle against herpes viruses, influenza, or poliovirus. Effects of blessed thistle (or chemicals in blessed thistle called lignans) against HIV are not clear. Human research of blessed thistle as a treatment for viral infections is lacking.
|
C |
Laboratory studies report no activity of blessed thistle against herpes viruses, influenza, or poliovirus. Effects of blessed thistle (or chemicals in blessed thistle called lignans) against HIV are not clear. Human research of blessed thistle as a treatment for viral infections is lacking.
|
C | * Key to grades
A: Strong scientific evidence for this use B: Good scientific evidence for this use C: Unclear scientific evidence for this use D: Fair scientific evidence for this use (it may not work) F: Strong scientific evidence against this use (it likley does not work)
| * Key to grades
A: Strong scientific evidence for this use B: Good scientific evidence for this use C: Unclear scientific evidence for this use D: Fair scientific evidence for this use (it may not work) F: Strong scientific evidence against this use (it likley does not work)
| Tradition / Theory
The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
Dosing
Adults (over 18 years old)
- Tea, tinctures, and liquid extracts are available. Traditional doses include 1.5 to 3 grams of dried blessed thistle flowering tops steeped in 150 milliliters of boiling water taken three times daily or 1 to 3 teaspoons of dried blessed thistle herb in one cup of boiling water for 5 to 15 minutes taken three times daily (sometimes recommended to be used 30 minutes before meals). 1.5 to 10 milliliters of other preparations have been taken by mouth up to three times daily. May be bitter in taste.
Safety
The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.
Interactions
Interactions with Drugs
- Traditionally, blessed thistle is believed to stimulate stomach acid secretion and it may reduce the effectiveness of drugs such as cimetidine (Tagamet?), famotidine (Pepcid?), nizatidine (Axid?), or ranitidine (Zantac?).
- Based on laboratory studies, blessed thistle may increase the risk of bleeding when taken with drugs that also increase the risk of bleeding (although effects in humans are not known). Some examples include aspirin, anticoagulants ("blood thinners") such as warfarin (Coumadin?) or heparin, anti-platelet drugs such as clopidogrel (Plavix?), and non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin?, Advil?) or naproxen (Naprosyn?, Aleve?).
- Many tinctures contain high levels of alcohol and may cause nausea or vomiting when taken with metronidazole (Flagyl?) or disulfiram (Antabuse?).
Attribution
-
This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).
Bibliography
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Yang L, Lin S, Yang T, et al. Synthesis of anti-HIV activity of dibenzylbutyrolactone lignans. Bioorg Med Chem Lett 1996;6(8):941-944.