Noni chinois

Related Terms

1,2-Dihydroxy-3-methylanthraquinone, 1,3,8-trihydroxy-2-methoxy-anthraquinone, 1,6-dihydroxy-2,4-dimethoxyanthraquinone, 1,6-dihydroxy-2-methoxyanthraquinone, 1F-fructofuranosylnystose, 1-hydroxy-2-methoxyanthraquinone, 1-hydroxy-2-methylanthraquinone, 1-hydroxyanthraquinone, 2,4-ethylcholesterol, 2-hydroxy-1-methoxy-anthraquinone, 2-hydroxymethyl-3-hydroxyanthraquinone, 2-methoxyanthraquinone, 2-methyl-anthraquinone, arabinose, Ba kich, ba-ji-tian (Chinese), beta-sitosterol, bois douleur, canarywood, cheese fruit, fructan, galactose, galacturonic acid, hagekiten (Japanese), hai ba ji (Chinese), Hawaiian noni, heptasaccharide, hexasaccharide, hog apple, Indian mulberry, Indian noni, luoling (Chinese - Singapore, Taiwan), mengkudu (Malay), menkoedoe, monotropein, mora de la India (Spanish), Morinda officinalis How., morinda root, Morindae radix, morindolide, morofficinaloside, mulberry, nhau, noni, noni juice, nono (French - Tahiti), nonu, nystose, pa chi t'ien (Chinese), pa kit tian (Chinese), p'agukch'on (Korean), pau-azeitona (Portuguese), physcion, rotten cheese fruit, Rubiaceae (family), rubiadin, rubiadin-1-methyl ether, ruibarbo caribe (Spanish), scopoletin, succinic acid, Tahitian noni juice, ura, wild pine, wu ning (Chinese - Singapore).
Selected combination products: EquiguardT (Morinda officinalis, Epimedium brevicomum Maxim., Schisandra chinensis Baill., Ligustrum lucidum Ait., Cuscuta chinensis Lam., Psoralea corylifolia, and Astragalus membranaceus Bge.); WKSY (Morinda officinalis, radix aconiti Lateralis preparata, herba Epimedii, Curculigo orchioides Gaertn., Cinnamomum cassia Presl, rhizoma Zingiberis, Codonopsis pilosula, radix Astragali, radix Rehmanniae praeparata, Plastrum testudinis, pericarpium Citri reticulatae, Amomum villosum Lour., and Glycyrrhiza uralensis Fisch.); Er-Xian Decoction (EXD), a Chinese medicine formula, composed of Curculigo orchioides Gaertn., Epimedium brevicornum Maxim., Morinda officinalis, Anemarrhenae asphodeloides Bge., Phellodendron chinense Schneid., and Angelica sinensis Diels.

Background

Ba ji tian, also known as Morinda officinalis, has a slightly curved, yellowish-gray root that is odorless and sweet to slightly sour in taste. This root may be stir-fried and eaten, or it may be used as medicine.
The root of Morinda officinalis has been used in traditional Chinese medicine since ancient times. It is believed to strengthen the bones and tendons, as well as treat infertility, missing menstrual periods, blood clots during menstruation, and other sexual health problems. The root may also relieve symptoms of back pain and muscular atrophy, a condition in which muscle wastes away. The fruit of Morinda officinalis is called the noni berry and has gained popularity in the United States and other Western countries.
Ba ji tian may have benefits for patients with cancer, depression, fatigue, inflammation, osteoporosis, memory problems, high blood glucose, or kidney disease. However, more studies are needed to confirm the use of Morinda officinalis in medicine. At this time, there is a lack of evidence to support the effectiveness of Morinda officinalis for any condition.

Evidence Table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. GRADE *
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. GRADE *


One study suggested that an herbal solution containing Morinda officinalis may improve symptoms of schizophrenia, a mental disorder. Larger, controlled studies for longer durations are needed to evaluate this finding.

 C


One study suggested that an herbal solution containing Morinda officinalis may improve symptoms of schizophrenia, a mental disorder. Larger, controlled studies for longer durations are needed to evaluate this finding.

 C
* Key to grades

A: Strong scientific evidence for this use
B: Good scientific evidence for this use
C: Unclear scientific evidence for this use
D: Fair scientific evidence for this use (it may not work)
F: Strong scientific evidence against this use (it likley does not work)
* Key to grades

A: Strong scientific evidence for this use
B: Good scientific evidence for this use
C: Unclear scientific evidence for this use
D: Fair scientific evidence for this use (it may not work)
F: Strong scientific evidence against this use (it likley does not work)

Tradition / Theory

The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.

Dosing

Adults (18 years and older)
There is no proven safe or effective dose for ba ji tian in adults.

Safety

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

Interactions

Interactions with Drugs
Ba ji tian may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. People taking insulin or drugs for diabetes by mouth should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Because ba ji tian contains estrogen-like chemicals, the effects of other agents believed to have estrogen-like properties may be altered.
Ba ji tian may also interact with agents that affect the immune system, anticancer agents, antidepressants, anti-inflammatory agents, calcium salts, depressants, osteoporosis agents, and stimulants.

Attribution

This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).

Bibliography

Chang, M. S., Kim, W. N., Yang, W. M., Kim, H. Y., Oh, J. H., and Park, S. K. Cytoprotective effects of Morinda officinalis against hydrogen peroxide-induced oxidative stress in Leydig TM3 cells. Asian J Androl 2008;10(4):667-674.
Choi, J., Lee, K. T., Choi, M. Y., Nam, J. H., Jung, H. J., Park, S. K., and Park, H. J. Antinociceptive anti-inflammatory effect of Monotropein isolated from the root of Morinda officinalis. Biol Pharm Bull 2005;28(10):1915-1918.
Cui, C., Yang, M., Yao, Z., Cao, B., Luo, Z., Xu, Y., and Chen, Y. [Antidepressant active constituents in the roots of Morinda officinalis How]. Zhongguo Zhong.Yao Za Zhi 1995;20(1):36-3.
Hsieh TC and Wu JM. Ethanolic extracts of herbal supplement Equiguard (TM) suppress growth and control gene expression in CWR22Rv1 cells representing the transition of prostate cancer from androgen dependence to hormone refractory status. International Journal of Oncology 2008;32(1):209-219.
Kim, I. T., Park, H. J., Nam, J. H., Park, Y. M., Won, J. H., Choi, J., Choe, B. K., and Lee, K. T. In-vitro and in-vivo anti-inflammatory and antinociceptive effects of the methanol extract of the roots of Morinda officinalis. J Pharm Pharmacol 2005;57(5):607-615.
Li, J., Zhang, H. L., Wang, Z., Liang, Y. M., Jiang, L., Ma, W., and Yang, D. P. [Determination content of the antidepressant extraction and analysis the trace elements from Morinda officinalis]. Zhong.Yao Cai. 2008;31(9):1337-1340.
Li, N., Qin, L. P., Han, T., Wu, Y. B., Zhang, Q. Y., and Zhang, H. Inhibitory effects of morinda officinalis extract on bone loss in ovariectomized rats. Molecules. 2009;14(6):2049-2061.
Li, Y. F., Gong, Z. H., Yang, M., Zhao, Y. M., and Luo, Z. P. Inhibition of the oligosaccharides extracted from Morinda officinalis, a Chinese traditional herbal medicine, on the corticosterone induced apoptosis in PC12 cells. Life Sci 1-10-2003;72(8):933-942.
Li, Y. F., Liu, Y. Q., Yang, M., Wang, H. L., Huang, W. C., Zhao, Y. M., and Luo, Z. P. The cytoprotective effect of inulin-type hexasaccharide extracted from Morinda officinalis on PC12 cells against the lesion induced by corticosterone. Life Sci 8-13-2004;75(13):1531-1538.
Li, Y. F., Yuan, L., Xu, Y. K., Yang, M., Zhao, Y. M., and Luo, Z. P. Antistress effect of oligosaccharides extracted from Morinda officinalis in mice and rats. Acta Pharmacol Sin. 2001;22(12):1084-1088.
Qiao, Z. S., Wu, H., and Su, Z. W. [Comparison with the pharmacological actions of Morinda officinalis, Damnacanthus officinarum and Schisandra propinqua]. Zhong.Xi.Yi.Jie.He.Za Zhi 1991;11(7):415-7, 390.
Soon, Y. Y. and Tan, B. K. Evaluation of the hypoglycemic and anti-oxidant activities of Morinda officinalis in streptozotocin-induced diabetic rats. Singapore Med J 2002;43(2):077-085.
Wu, Y. J., Shi, J., Qu, L. B., Li, F. F., Li, X. J., and Wu, Y. M. [Determination of antioxidation of the extract from Chinese medicine Morinda officinalis How by flow injection chemiluminescence and spectroscopy]. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. 2006;26(9):1688-1691.
Zhang, H. L., Li, J., Li, G., Wang, D. M., Zhu, L. P., and Yang, D. P. Structural characterization and anti-fatigue activity of polysaccharides from the roots of Morinda officinalis. Int J Biol Macromol. 4-1-2009;44(3):257-261.
Zhang, Z. Q., Yuan, L., Yang, M., Luo, Z. P., and Zhao, Y. M. The effect of Morinda officinalis How, a Chinese traditional medicinal plant, on the DRL 72-s schedule in rats and the forced swimming test in mice. Pharmacol Biochem Behav 2002;72(1-2):39-43.