Dogwood

Dogwood/Drug Interactions:

  • Antidiabetic agentsAntidiabetic agents: Based on in vitro studies, dogwood may protect against diabetic complications (5; 6).
  • Antilipemic agentsAntilipemic agents: Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of total cholesterol/high density lipoprotein cholesterol and triglycerides, and increase high density lipoprotein cholesterol and apoA levels (3).
  • Antineoplastic agentsAntineoplastic agents: Based on an in vitro study, water extracts of Cornus officinalis Sieb. et Zuce may have antineoplastic activity (1).
  • AntioxidantsAntioxidants: Based on in vitro study, extracts of Cornus officinalis Sieb. et Zuce may have antioxidant activity (1; 2).
  • Antiretroviral agentsAntiretroviral agents: Based on in vitro study of HIV-1 reverse transcriptase, Cornus kousa MeOH extracts (stem and leaf) may have inhibitory activity on RNA-dependent DNA polymerase activity (7).
  • ContraceptivesContraceptives: Based on a case report, dogwood may increase fertility in infertile women (4). Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH and increase estradiol levels (3).
  • EstrogensEstrogens: Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH and increase estradiol levels (3).
  • Fertility agentsFertility agents: Based on an in vitro study, aqueous extracts of dried Cornus officinalis fruits may increase sperm motility (9). Based on a case report, dogwood may increase fertility in infertile women (4). Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH and increase estradiol levels (3).

    • Dogwood/Herb/Supplement Interactions:

  • AntilipemicsAntilipemics: Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of total cholesterol/high density lipoprotein cholesterol and triglycerides, and increase high density lipoprotein cholesterol and apoA levels (3).
  • AntineoplasticsAntineoplastics: Based on an in vitro study, water extracts of Cornus officinalis Sieb. et Zuce may have antineoplastic activity (1).
  • AntioxidantsAntioxidants: Based on in vitro study, extracts of Cornus officinalis Sieb. et Zuce may have antioxidant activity (1; 2).
  • AntiviralsAntivirals: Based on in vitro study of HIV-1 reverse transcriptase, Cornus kousa MeOH extracts (stem and leaf) may have inhibitory activity on RNA-dependent DNA polymerase activity (7).
  • ContraceptivesContraceptives: Based on a case report, dogwood may increase fertility in infertile women (4). Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH and increase estradiol levels (3).
  • Fertility agentsFertility agents: Based on an in vitro study, aqueous extracts of dried Cornus officinalis fruits may increase sperm motility (9). Based on a case report, dogwood may increase fertility in infertile women (4). Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH and increase estradiol levels (3).
  • HypoglycemicsHypoglycemics: Based on in vitro studies, dogwood may protect against diabetic complications (5; 6).
  • PhytoestrogensPhytoestrogens: Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH and increase estradiol levels (3).

    • Dogwood/Food Interactions:

  • Insufficient available evidence.

    • Dogwood/Lab Interactions:

  • EstrogenEstrogen: Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may increase estradiol levels (3).
  • Follicle stimulating hormone (FSH)Follicle stimulating hormone (FSH): Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of FSH (3).
  • HIV viral loadHIV viral load: Based on in vitro study of HIV-1 reverse transcriptase, Cornus kousa MeOH extracts (stem and leaf) may have inhibitory activity on RNA-dependent DNA polymerase activity (7).
  • Serum lipid levelsSerum lipid levels: Based on a clinical trial of postmenopausal women using dandi tablet (Rehmannia root 24g, dogwood fruit 9g, poria 9g, water plantain 9g, tuber peony bark 9g, Chinese yam 12g, red sage 15g), dogwood fruit may lower levels of total cholesterol/high density lipoprotein cholesterol and triglycerides, and increase high density lipoprotein cholesterol and apoA levels (3).