Horse heal
Elecampane/Drug Interactions:
AlcoholAlcohol: Traditionally, elecampane has been added to white wine for the treatment of bronchitis (27).AntibioticsAntibiotics: Based on an in vitro study, elecampane may have moderate antibacterial activity against Staphylococcus aureus, Enterococcus faecalis, and Escherischia coli (3; 28). Antidiabetic agentsAntidiabetic agents: Secondary sources indicate that elecampane infusion induced a hyperglycemic (large doses) or a hypoglycemic effect in an animal model. Inula racemosa (a related species) extract lowered plasma insulin and glucose and counteracted adrenaline-induced hyperglycemia in animal models (2). Thus, it is possible that elecampane has additive or opposite effects with glucose modulating agents in humans. AntifungalsAntifungals: Based on an in vitro study, elecampane may have moderate antifungal activity against Pseudomonas aeruginosa and Candida albicans (3). AntihypertensivesAntihypertensives: Secondary sources indicate that elecampane infusion induced a hypotensive effect in an animal model. Thus, it is possible that elecampane has additive effects with other hypotensives in humans.Antineoplastic agentsAntineoplastic agents: In vitro, extracts from elecampane suppressed the growth of cultured human lymphoblastoid Raji cells (16). Antiproliferative action of elecampane was also found in other in vitro studies (13; 17; 18; 19). Thus, there is a potential for additive effects between elecampane and anticancer agents in humans. AntioxidantsAntioxidants: Based on an animal study using the underground part of elfwort (Inula helenium), elecampane may have antioxidant properties (4). Antiparasitic agentsAntiparasitic agents: Based on an in vitro study, elecampane may have antiparasitic activity in Ascaris lumbricoides and Clonorchis sinensis (5; 6; 7). Antispasmodic agentsAntispasmodic agents: In an animal model, the volatile oil of elecampane root had relaxant effects on tracheal and ileal smooth muscles (8). Thus, it is possible that elecampane has additive effects with other agents that induce muscle relaxation. Cardiovascular agentsCardiovascular agents: In humans, Inula racemosa (a related species) prevented ST-segment depression and T-wave inversion in patients with ischemic heart disease (2) and had a beneficial effect on angina pectoris (1). Inula racemosa extract exhibited negative inotropic and chronotropic effects on a frog heart (2) and prevented experimentally-induced myocardial infarction in a rat model (14). Thus, elecampane may have additive effects with cardiac agents in humans. LaxativesLaxatives: According to a secondary source, an elecampane multi-ingredient compound (Padma Lax? containing ginger and elecampane) may have laxative effects (13). Thus, there is a potential for additive effects between elecampane and laxative agents in humans. SedativesSedatives: Secondary sources indicate that elecampane infusion induced a sedative effect in an animal model. Thus, it is possible that elecampane has additive effects with other sedatives in humans.Elecampane/Herb/Supplement Interactions:
AntibacterialsAntibacterials: Based on an in vitro study, elecampane may have moderate antibacterial activity against Staphylococcus aureus, Enterococcus faecalis, and Escherischia coli (3; 28). AntifungalsAntifungals: Based on an in vitro study, elecampane may have moderate antifungal activity against Pseudomonas aeruginosa and Candida albicans (3). AntineoplasticsAntineoplastics: In vitro, extracts from elecampane suppressed the growth of cultured human lymphoblastoid Raji cells (16). Antiproliferative action of elecampane was also found in other in vitro studies (13; 17; 18; 19). Thus, there is a potential for additive effects between elecampane and anticancer agents in humans. AntioxidantsAntioxidants: Based on an animal study using the underground part of elfwort (Inula helenium), elecampane may have antioxidant properties (4). Antiparasitic agentsAntiparasitic agents: Based on an in vitro study, elecampane may have antiparasitic activity in Ascaris lumbricoides and Clonorchis sinensis (5; 6; 7). AntispasmodicsAntispasmodics: In an animal model, the volatile oil of elecampane root had relaxant effects on tracheal and ileal smooth muscles (8). Thus, it is possible that elecampane has additive effects with other agents that induce muscle relaxation. Cardioactive herbsCardioactive herbs: In humans, Inula racemosa (a related species) prevented ST-segment depression and T-wave inversion in patients with ischemic heart disease (2) and had a beneficial effect on angina pectoris (1). Inula racemosa extract exhibited negative inotropic and chronotropic effects on a frog heart (2) and prevented experimentally-induced myocardial infarction in a rat model (14). Thus, elecampane may have additive effects with cardiac agents in humans. EchinaceaEchinacea: Based on secondary sources, Echinacea and osha (Ligusticum porteri) root have been used in combination with elecampane for respiratory ailments.GingerGinger: According to a secondary source, an elecampane multi-ingredient compound (Padma Lax? containing ginger and elecampane) may have laxative effects (13). Thus, there is a potential for additive effects between elecampane and ginger as laxative agents in humans. In vitro, ginger and elecampane, in combination as ingredients in Padma Lax?, had antiproliferative effects in tumor cells in culture. Thus, there is a potential for additive effects between elecampane and ginger as anti-cancer agents in humans. HypoglycemicsHypoglycemics: Secondary sources indicate that elecampane infusion induced a hyperglycemic (large doses) or a hypoglycemic effect in an animal model. Inula racemosa (a related species) extract lowered plasma insulin and glucose and counteracted adrenaline-induced hyperglycemia in animal models (2). Thus, it is possible that elecampane has additive or opposite effects with glucose modulating agents in humans. HypotensivesHypotensives: Secondary sources indicate that elecampane infusion induced a hypotensive effect in an animal model. Thus, it is possible that elecampane has additive effects with other hypotensives in humans.LaxativesLaxatives: According to a secondary source, an elecampane multi-ingredient compound (Padma Lax? containing ginger and elecampane) may have laxative effects (13). Thus, there is a potential for additive effects between elecampane and laxative agents in humans. Osha Osha (Ligusticum porteri): Based on secondary sources, Echinacea and osha (Ligusticum porteri) root have been used in combination with elecampane for respiratory ailments.SedativesSedatives: Secondary sources indicate that elecampane infusion induced a sedative effect in an animal model. Thus, it is possible that elecampane has additive effects with other sedatives in humans.Elecampane/Food Interactions:
GingerGinger: According to a secondary source, an elecampane multi-ingredient compound (Padma Lax? containing ginger and elecampane) has been suggested to have laxative effects (13). Thus, there is a potential for additive effects between elecampane and ginger as laxative agents in humans. In vitro, ginger and elecampane, in combination as ingredients in Padma Lax?, had antiproliferative effects in tumor cells in culture. Thus, there is a potential for additive effects between elecampane and ginger as anticancer agents in humans. Elecampane/Lab Interactions:
Serum glucose levelsSerum glucose levels: Secondary sources indicate that elecampane infusion induced a hyperglycemic (large doses) or a hypoglycemic effect in an animal model. In an animal model, Inula racemosa (a related species) extract lowered plasma glucose and counteracted adrenaline-induced hyperglycemia (2). Thus, it is possible that elecampane has effects on glucose levels in humans. Serum insulin levelsSerum insulin levels: In an animal model, Inula racemosa extract lowered plasma insulin (2). Thus it is possible that elecampane has effects on insulin levels in humans.