Hypoxis hemerocallidea

African wild potato/Drug Interactions:

  • Antidiabetic agentsAntidiabetic agents: Based on animal data, African wild potato appears to lower blood sugar (3). Therefore, concurrent use with anti-diabetic drugs may possibly increase the risk for hypoglycemia.
  • AntiretroviralsAntiretrovirals: Inhibition of the P-glycoprotein may occur when taking extracts of the African wild potato, putting patients with HIV/AIDS at risk of treatment failure, viral resistance or drug toxicity (4).
  • Cytochrome P450 metabolized agentsCytochrome P450 metabolized agents: Extracts of the African wild potato have significant effects on cytochrome P450 3A4 metabolism (4). Therefore, taking African wild potato with drugs metabolized by this enzyme system may possibly alter drug levels.
  • Nephrotoxic drugsNephrotoxic drugs: Aqueous extracts of the African wild potato may impair kidney function (2).
  • DiureticsDiuretics: Aqueous extracts of the African wild potato may reduce urination and excretion of potassium and sodium (2).

    • African wild potato/Herb/Supplement Interactions:

  • AntiviralsAntivirals: Inhibition of the P-glycoprotein may occur by taking extracts of the African wild potato putting patients with HIV/AIDS at risk of treatment failure with viral resistance or drug toxicity (4).
  • Cytochrome P450 metabolized herbs and supplementsCytochrome P450 metabolized herbs and supplements: Extracts of the African wild potato have significant effects on cytochrome P450 3A4 metabolism (4). Therefore, taking African wild potato with herbs and supplements metabolized by this enzyme system may possibly alter drug levels.
  • DiureticsDiuretics: Aqueous extracts of the African wild potato may reduce urination and excretion of potassium and sodium (2).
  • HypoglycemicsHypoglycemics: Based on animal data, African wild potato appears to lower blood sugar (3). Therefore, concurrent use with anti-diabetic herbs and supplements may possibly increase the risk for hypoglycemia.

    • African wild potato/Food Interactions:

  • Insufficient available evidence.

    • African wild potato/Lab Interactions:

  • Serum glucoseSerum glucose: African wild potato appears to have an effect on blood sugar based on rat data (3).