Lobelia

Lobelia/Drug Interactions:

  • AlcoholAlcohol: According to animal research, lobelia may cause CNS depressant effects (13).
  • Antiasthma drugsAntiasthma drugs: According to in vitro research, lobelia may act as a respiratory stimulant (1).
  • Antidepressant agentsAntidepressant agents: According to animal research, beta-amyrin palmitate, a constituent of lobelia, may have antidepressant activity (6; 13; 7). In animal research, beta-amyrin palmitate displayed antidepressant effects similar to the effects of mianserin and imipramine (6; 13).
  • AntihypertensivesAntihypertensives: According to animal research, lobelia may have hypotensive effects (13).
  • Anti-inflammatory agentsAnti-inflammatory agents: In an in vitro study, Lobelia laxiflora L. contained piperidine alkaloids (racem. cis-8,10-diethyl-3,4-dehydrolobelidiol, racem. trans-8-ethyl-10-phenyl-3,4-dehydrolobelidiol, and racem. cis-8-ethyl-10-phenyl-3,4-dehydrolobelidiol), which have been shown to inhibit complement activation and thus prevent the inflammatory process (8).
  • CNS depressantsCNS depressants: According to animal research, lobelia may cause CNS depressant effects (13).
  • DiureticsDiuretics: In animal research, lobelia has displayed antidiuretic effects (17).
  • NicotineNicotine: According to in vitro research, lobeline, a constituent of lobelia, may have similar effects to nicotine (4).

    • Lobelia/Herb/Supplement Interactions:

  • Antiasthma herbs and supplementsAntiasthma herbs and supplements: According to in vitro research, lobelia may act as a respiratory stimulant (1).
  • Antidepressant herbs and supplementsAntidepressant herbs and supplements: According to animal research, beta-amyrin palmitate, a constituent of lobelia, may have antidepressant activity (6; 13; 7).
  • Anti-inflammatory herbsAnti-inflammatory herbs: In an in vitro study, Lobelia laxiflora L. contained piperidine alkaloids (racem. cis-8,10-diethyl-3,4-dehydrolobelidiol, racem. trans-8-ethyl-10-phenyl-3,4-dehydrolobelidiol, and racem. cis-8-ethyl-10-phenyl-3,4-dehydrolobelidiol), which have been shown to inhibit complement activation and thus prevent the inflammatory process (8).
  • ChromiumChromium: Because lobelia is considered a source of chromium, it may have additive effects when combined with herbs that also contain chromium, including sand immortelle, foxglove, Alexandrian laurel, Greek valerian, marsh cudweed, and Adenostyles (12).
  • DiureticsDiuretics: In animal research, lobelia has displayed antidiuretic effects (17).
  • HypotensivesHypotensives: According to animal research, lobelia may have hypotensive effects (13).
  • SedativesSedatives: According to animal research, lobelia may cause CNS depressant effects (13).
  • TobaccoTobacco: According to in vitro research, lobeline, a constituent of lobelia, may have similar effects to nicotine (4).

    • Lobelia/Food Interactions:

  • TeasTeas: According to secondary sources, lobelia may have additive sedative effects with certain tea products.

    • Lobelia/Lab Interactions:

  • Blood pressureBlood pressure: According to animal research, lobelia may have blood pressure-lowering effects (13).