Picrorhiza kurroa

Katuka/Drug Interactions:

  • Antidiabetic agentsAntidiabetic agents: Based on a study in normal and alloxan-induced diabetic rats, Picrorhiza kurroa may lower blood glucose in basal conditions and after a heavy glucose load (1).
  • Antilipemic agentsAntilipemic agents: Based on a study of hyperlipemic mice on a high fat diet, Picrorhiza kurroa may significantly reduce low density lipoprotein (LDL), triglyceride, and total cholesterol levels (3). However, serum HDL levels may not be affected.
  • Antineoplastic agentsAntineoplastic agents: Based on studies in mice and other animals with induced tumors, katuka extract may have antitumor and anticarcinogenic properties (9; 4).
  • Hepatotoxic agentsHepatotoxic agents: Based on studies of hyperlipemic mice, alloxan-treated rats, and other animals, Picrorhiza kurroa may reduce liver weight, serum aspartate transferase (AST), alanine transferase (ALT), blood urea nitrogen (BUN), glutathione S-transferase, gamma-glutamyl transpeptidase, glutathione, or aniline hydroxylase levels (3; 1; 4; 5).
  • ImmunosuppressantsImmunosuppressants: Based on rats administered with alloxan, Picrorhiza kurroa may inhibit leukopenia (1).

    • Katuka/Herb/Supplement Interactions:

  • AntilipemicsAntilipemics: Based on a study of hyperlipemic mice on a high fat diet, Picrorhiza kurroa may significantly reduce low density lipoprotein (LDL), triglyceride, and total cholesterol levels (3). However, serum HDL levels may not be affected.
  • AntineoplasticsAntineoplastics: Based on studies in mice and other animals with induced tumors, katuka extract may have antitumor and anticarcinogenic properties (9; 4).
  • AntioxidantsAntioxidants: Based on a study in alloxan-treated rats, Picrorhiza kurroa may have antioxidant properties (1).
  • Hepatotoxic herbsHepatotoxic herbs: Based on studies of hyperlipemic mice, alloxan-treated rats, and other animals, Picrorhiza kurroa may reduce liver weight, serum aspartate transferase (AST), alanine transferase (ALT), blood urea nitrogen (BUN), glutathione S-transferase, gamma-glutamyl transpeptidase, reduced glutathione, or aniline hydroxylase levels (3; 1; 4; 5).
  • HypoglycemicsHypoglycemics: Based on a study in normal and alloxan-induced diabetic rats, Picrorhiza kurroa may lower blood glucose in basal conditions and after a heavy glucose load (1).
  • ImmunosuppressantsImmunosuppressants: Based on rats administered with alloxan, Picrorhiza kurroa may inhibit leukopenia (1).
  • Indian gooseberry(Phyllanthus emblica)Indian gooseberry(Phyllanthus emblica): Based on a study of animals with hepatocarcinogenesis induced by N-nitrosodiethylamine (NDEA), a combination of Phyllanthus emblica, Phyllanthus amarus, and Picrorhiza kurroa extracts may reduce glutathione S-transferase, gamma-glutamyl transpeptidase, glutathione, or aniline hydroxylase levels (4).
  • Phyllanthus amarusPhyllanthus amarus: Based on a study of animals with hepatocarcinogenesis induced by N-nitrosodiethylamine (NDEA), a combination of Phyllanthus emblica, Phyllanthus amarus, and Picrorhiza kurroa extracts may reduce glutathione S-transferase, gamma-glutamyl transpeptidase, glutathione, or aniline hydroxylase levels (4).

    • Katuka/Food Interactions:

  • Insufficient available evidence.

    • Katuka/Lab Interactions:

  • Liver enzyme levelsLiver enzyme levels: Based on studies of hyperlipemic mice, alloxan-treated rats, and other animals, Picrorhiza kurroa may reduce liver weight, serum aspartate transferase (AST), alanine transferase (ALT), blood urea nitrogen (BUN), glutathione S-transferase, gamma-glutamyl transpeptidase, reduced glutathione, or aniline hydroxylase levels (3; 1; 4; 5).
  • Serum glucose levelsSerum glucose levels: Based on studies in normal rats and alloxan-induced diabetic rats, Picrorhiza kurroa may lower blood glucose in basal conditions or after a heavy glucose load (1).
  • Serum lipid levelsSerum lipid levels: Based on a study of hyperlipemic mice on a high fat diet, Picrorhiza kurroa may significantly reduce low-density lipoprotein (LDL), triglyceride, and total cholesterol levels (3). However, serum HDL levels may not be affected.
  • White blood cell countWhite blood cell count: Based on rats administered with alloxan, Picrorhiza kurroa may inhibit leukopenia (1).