Salba

Chia/Drug Interactions

  • AnticoagulantsAnticoagulants: In theory, the roots of Salvia hispanica may interact with warfarin, due to reported pharmacokinetic and pharmacodynamic interactions between the related Salvia miltiorrhiza (danshen) roots and warfarin (16; 17).
  • AntihypertensivesAntihypertensives: Salba? may lower blood pressure (8).
  • Antineoplastic agentsAntineoplastic agents: Salvia hispanica oil has been reported to inhibit tumor growth in a murine model of adenocarcinoma (7).
  • Cytochrome P450 metabolized agentsCytochrome P450 metabolized agents: Drug-metabolizing enzymes may be affected by extracts of Salvia hispanica, based on reported interactions between cytochrome P450 metabolized agents and Salvia miltiorrhiza (19).

    • Chia/Herb/Supplement Interactions

  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: In theory, the roots of chia Salvia hispanica may interact with other herbs that exhibit anticoagulant properties, such as Ginkgo biloba (ginkgo), Allium sativum (garlic), and Angelica sinensis (dong quai) (16).
  • AntineoplasticsAntineoplastics: A diet supplemented with Salvia hispanica seed oil has been reported to inhibit tumor growth in a murine model of adenocarcinoma (7).
  • AntioxidantsAntioxidants: According to Core Naturals LLC, Salba? contains a significant amount of antioxidants; therefore, Salvia hispanica seed may have additive effects when combined with other supplements that are antioxidants, such as vitamins A, C, and E.
  • Cytochrome P450 metabolized herbs and supplementsCytochrome P450 metabolized herbs and supplements: Drug-metabolizing enzymes may be affected by extracts of Salvia hispanica, based on reported interactions between cytochrome P450 metabolized agents and Salvia miltiorrhiza (19).
  • HypotensivesHypotensives: Because Salba? may lower blood pressure (8), it may interact with herbs and supplements that affect blood pressure such as omega-3 fatty acids, fish oil, and alpha-linolenic acid (ALA).
  • Omega-3 fatty acids, fish oil, alpha-linolenic acidOmega-3 fatty acids, fish oil, alpha-linolenic acid: Salvia hispanica seed may contain high amounts of omega-3 fatty acids, fiber, and alpha-linolenic acid (20).

    • Chia/Food Interactions

  • AntioxidantsAntioxidants: According to Core Naturals LLC, Salba? is rich in antioxidants; therefore, Salvia hispanica seed chia may have additive effects when combined with other foods that have significant amounts of antioxidants.

    • Chia/Lab Interactions

  • Blood pressureBlood pressure: In one study, Salba? significantly lowered systolic blood pressure in type 2 diabetic patients (8). Therefore, a diet containing Salvia hispanica seed may in theory affect blood pressure tests.
  • Coagulation panelCoagulation panel: The root extracts of Salvia columbariae (golden chia) and Salvia miltiorrhiza (danshen) are reported to contain compounds that act as anticoagulants; thus, the roots of Salvia hispanica may contain similar activity (1).