Salvia divinorum
Salvia/Drug Interactions:
Hallucinogenic agentsHallucinogenic agents: Salvia may have hallucinogenic effects (1). OpioidsOpioids: Based on mechanism of action, additive effects may occur with other opioid drugs (3; 4; 5; 6; 7; 8; 9; 10) Salvia/Herb/Supplement Interactions:
Hallucinogenic agentsHallucinogenic agents: Salvia may have hallucinogenic effects (1). Opioid-containing herbs (e.g., poppy)Opioid-containing herbs (e.g., poppy): Based on mechanism of action, additive effects may occur with other opioid herbs (3; 4; 5; 6; 7; 8; 9; 10) Salvia/Food Interactions:
Insufficient available evidence.Salvia/Lab Interactions:
Body temperatureBody temperature: Based on animal study, salvinorin A and salvinorinyl-2-propionate may reduce rectal body temperature, which is a similar effect as conventional kappa-opioid receptor agonists (1).