Spirogermanium

Germanium/Drug Interactions:

  • 5-fluorouracil5-fluorouracil: Two toxic deaths, both attributable to neutropenia and sepsis, were reported in a phase II trial studying spirogermanium in combination with 5-fluorouracil (42). Significant toxicity occurred in all seventeen patients, including three instances of Grade 3 or 4 hematologic toxicity (42).
  • AnalgesicsAnalgesics: An animal study suggested that Ge-132 (germanium sesquioxide) may enhance morphine analgesia in humans following both oral and intraperitoneal injection (21).

    • Germanium/Herb/Supplement Interactions:

  • Insufficient available evidence.

    • Germanium/Food Interactions:

  • Insufficient available evidence.

    • Germanium/Lab Interactions:

  • Insufficient available evidence.