Thryallis

Galphimia glauca/Drug Interactions:

  • Antianxiety drugsAntianxiety drugs: In human and animal research, Galphimia glauca and its constituents have been found to exert anxiolytic effects (19; 18; 21; 16).
  • AntihistaminesAntihistamines: In laboratory research, extracts of Galphimia glauca inhibited ConA-induced histamine release from human adenoidal mast cells (22).
  • AntineoplasticsAntineoplastics: according to in vivo evidence, Galphimia glauca extracts inhibited colon cancer cell line growth but did not display cytotoxic and genotoxic effects (10).
  • Antiplatelets and anticoagulantsAntiplatelets and anticoagulants: According to in vitro evidence, tetragalloyl quinic acid, an active constituent isolated from Galphimia glauca, may suppress thromboxane synthesis and thereby reduce platelet aggregation (17).
  • AntiprotozoalsAntiprotozoals: According to in vitro evidence, quercetin, a constituent of Galphimia glauca, exhibited weak antiprotozoal activity against Plasmodium falciparum, Trypanosoma brucei brucei, and Leishmania donovani (23).
  • CNS depressantsCNS depressants: According to in vitro evidence, galphimine B, a bioactive constituent and methanolic extract of the aerial plant of Galphimia glauca Cav. (Malpighiaceae), exhibited strong depressant activity on the nervous system (2).
  • VasodilatorsVasodilators: According to in vivo evidence, the aqueous extracts of Galphimia glauca leaves and flowers may inhibit the maximal contractile response induced by noradrenaline in rat aorta, which produced a vasorelaxant effect (24).
  • VasopressorsVasopressors: According to in vivo evidence, the aqueous extracts of Galphimia glauca leaves and flowers may inhibit the maximal contractile response induced by noradrenaline in rat aorta, which produced a vasorelaxant effect (24).
  • Galphimia glauca/Herb/Supplement Interactions:

  • AntihistaminesAntihistamines: Extracts of Thryallis glauca (Galphimia glauca) inhibited ConA-induced histamine release from human adenoidal mast cells (22).
  • AntineoplasticsAntineoplastics: According to in vivo evidence, Galphimia glauca extracts inhibited colon cancer cell line growth but did not display cytotoxic and genotoxic effects (10).
  • AntiparasiticsAntiparasitics: According to in vitro evidence, quercetin, a constituent of Galphimia glauca, exhibited weak antiprotozoal activity against Plasmodium falciparum, Trypanosoma brucei brucei, and Leishmania donovani (23).
  • Antiplatelets and anticoagulantsAntiplatelets and anticoagulants: According to in vitro evidence, tetragalloyl quinic acid, an active constituent isolated from Galphimia glauca, may suppress thromboxane synthesis and thereby reduce platelet aggregation (17).
  • SedativesSedatives: According to in vitro evidence, galphimine B, a bioactive constituent and methanolic extract of the aerial plant of Galphimia glauca Cav. (Malpighiaceae), exhibited strong depressant activity on the nervous system (2). In human and animal research, Galphimia glauca and its constituents have been found to exert anxiolytic effects (19; 18; 21; 16).
  • timulantsStimulants: According to in vitro evidence, galphimine B, a bioactive constituent and methanolic extract of the aerial plant of Galphimia glauca Cav. (Malpighiaceae), exhibited strong depressant activity on the nervous system (2). Theoretically, Galphimia glauca may interfere with the effects of CNS stimulants.
  • VasoconstrictorsVasoconstrictors: According to in vivo evidence, the aqueous extracts of Galphimia glauca leaves and flowers may inhibit the maximal contractile response induced by noradrenaline in rat aorta, which produced a vasorelaxant effect (24).
  • VasodilatorsVasodilators: According to in vivo evidence, the aqueous extracts of Galphimia glauca leaves and flowers may inhibit the maximal contractile response induced by noradrenaline in rat aorta, which produced a vasorelaxant effect (24).
  • Galphimia glauca/Food Interactions:

  • Insufficient available evidence.
  • Galphimia glauca/Lab Interactions:

  • Insufficient available evidence.