Thuja occidentalis

Thuja/Drug Interactions:

  • AntibioticsAntibiotics: According to human research, the combination product Esberitox? (containing a dry extract 4-9:1 blend of Baptisia tinctoria (wild indigo) root, Echinacea purpurea and pallida (coneflower) root, and Thuja occidentalis (white cedar) leaf) may be beneficial in combination with antibiotics to improve recovery and prevent immune system impairment caused by antibiotics (9).
  • AntineoplasticsAntineoplastics: According to in vitro evidence, Thuja may have antitumor activity (11; 4). Theoretically, Thuja may interact with antineoplastic agents, but it is unclear if these interactions are synergistic or antagonistic.
  • AntiretroviralsAntiretrovirals: According to in vitro evidence of inhibition of HIV-1-specific antigens and reverse transcriptase (5), theoretically, Thuja may act synergistically with antiretroviral medications.
  • HepatotoxinsHepatotoxins: There have been anecdotal reports of liver toxicity.
  • ImmunosuppressantsImmunosuppressants: According to in vitro evidence, Thuja may have immunostimulating properties (5; 6; 11). Theoretically, concurrent use may interfere with immunosuppressive therapy.

    • Thuja/Herb/Supplement Interactions:

  • AntibacterialsAntibacterials: According to human research, the combination product Esberitox? (containing a dry extract 4-9:1 blend of Baptisia tinctoria (wild indigo) root, Echinacea purpurea and pallida (coneflower) root, and Thuja occidentalis (white cedar) leaf) may be beneficial in combination with antibiotics to improve recovery and prevent immune system impairment caused by antibiotics (9).
  • AntineoplasticsAntineoplastics: According to in vitro evidence, Thuja may have antitumor activity (11; 4). Theoretically, Thuja may interact with antineoplastic agents, but it is unclear if these interactions are synergistic or antagonistic.
  • AntiretroviralsAntiretrovirals: According to in vitro evidence of inhibition of HIV-1-specific antigens and reverse transcriptase (5), theoretically, Thuja may act synergistically with antiretroviral medications.
  • HepatotoxinsHepatotoxins: There have been anecdotal reports of liver toxicity.
  • ImmunomodulatorsImmunomodulators: According to in vitro evidence, Thuja may have immunostimulating properties (5; 6; 11). Theoretically, concurrent use may have additive effects.
  • Thujone-containing herbsThujone-containing herbs: Anecdotally, Thuja theoretically could act synergistically or additively with other thujone-containing herbs and supplements.

    • Thuja/Food Interactions:

  • Insufficient available evidence.

    • Thuja/Lab Interactions:

  • HIV-1-specific antigensHIV-1-specific antigens: In vitro evidence indicates that Thuja appears to inhibit HIV-1-specific antigens and reverse transcriptase (5).
  • Immune function testsImmune function tests: In vitro,Thuja polysaccharide g-fraction (TPSg) induced the CD4+ fraction of the human peripheral blood T cell subset and induced cytokine production, including interleukin (IL)-1, IL-6, and TNF-alpha (5; 6; 11).