Tussilago farfara

Coltsfoot/Drug Interactions:

  • Antiasthma drugsAntiasthma drugs: Based on a clinical study, a Chinese herbal concoction containing Tussilago farfara L. and several other herbs improved maximum expiratory flow-volume (MEFV) curvese (4).
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: Based on a laboratory study, Tussilago farfara L. may inhibit platelet activating factor (PAF) (3).
  • AntihypertensivesAntihypertensives: Based on animal studies, tussilagone extracted from coltsfoot may have a dose dependent pressor effect (5).
  • Anti inflammatory agentsAnti inflammatory agents: Based on traditional use, coltsfoot may have anti-inflammatory activity when applied topically to dermatological inflammatory conditions, including eczema.
  • AntitussivesAntitussives: Based on traditional use, coltsfoot may be a cough suppressant/expectorant.
  • Calcium channel blockersCalcium channel blockers: Based on laboratory study, Tussilago farfara L. may inhibit Ca2+ channel blocker binding (3).
  • ExpectorantsExpectorants: Based on traditional use, coltsfoot may be a cough suppressant/expectorant.
  • Hepatotoxic agentsHepatotoxic agents: Due to its pyrrolizidine alkaloid content, coltsfoot may potentially be toxic to the liver when consumed in large doses (2; 1).
  • Hypertensive drugsHypertensive drugs: Based on animal studies, tussilagone extracted from coltsfoot may have a dose dependent pressor effect (5).

    • Coltsfoot/Herb/Supplement Interactions:

  • Antiasthma herbs and supplementsAntiasthma herbs and supplements: Based on a clinical study, a Chinese herbal concoction containing Tussilago farfara and several other herbs improved maximum expiratory flow-volume (MEFV) curvese (4).
  • Anticoagulants and antiplateletsAnticoagulants and antiplatelets: Based on a laboratory study, Tussilago farfara L. may inhibit platelet activating factor (PAF) (3).
  • Anti inflammatory herbsAnti inflammatory herbs: Based on traditional use, coltsfoot may have anti-inflammatory activity when applied topically to dermatological inflammatory conditions, including eczema.
  • AntitussivesAntitussives: Based on traditional use, coltsfoot may be a cough suppressant/expectorant.
  • Cardioactive herbsCardioactive herbs: Based on laboratory study, Tussilago farfara L. may inhibit Ca2+ channel blocker binding (3).
  • ExpectorantsExpectorants: According to secondary sources, coltsfoot has been used as a cough suppressant/expectorant for the treatment of respiratory conditions. Concomitant use may potentially enhance the effects of cough suppressant/expectorant agents.
  • Hepatotoxic herbsHepatotoxic herbs: Due to its pyrrolizidine alkaloid content, coltsfoot may potentially be toxic to the liver when consumed in large doses (2; 1).
  • HypertensivesHypertensives: Based on animal studies, tussilagone extracted from coltsfoot may have a dose dependent pressor effect (5).
  • HypotensivesHypotensives: Based on animal studies, tussilagone extracted from coltsfoot may have a dose dependent pressor effect (5).
  • Pyrrolizidine alkaloid containing herbsPyrrolizidine alkaloid containing herbs: Coltsfoot contains pyrrolizidine alkaloids (1).

    • Coltsfoot/Food Interactions:

  • Insufficient available evidence.

    • Coltsfoot/Lab Interactions:

  • Coagulation panelCoagulation panel: Based on a laboratory study, Tussilago farfara L. may inhibit platelet activating factor (PAF) (3).
  • Liver panelLiver panel: Due to its pyrrolizidine alkaloid content, coltsfoot may potentially be toxic to the liver, which may affect liver enzyme levels, when consumed in large doses (2; 1).
  • Vital signsVital signs: Based on animal studies, tussilagone extracted from coltsfoot may have a dose dependent pressor effect (5). Based on laboratory study, Tussilago farfara L. may inhibit Ca2+ channel blocker binding (3).