Water hemlock

Water hemlock/Drug Interactions:

  • Anticonvulsant agentsAnticonvulsant agents: Based on case reports, oral ingestion may cause an explosive illness with seizures and convulsions (3; 7; 5; 6), neurologic lethargy (2), or unconsciousness (5; 2) that may lead to death (1; 7; 2; 6).
  • Cardiac glycosidesCardiac glycosides: Based on case reports, oral ingestion may cause an explosive illness with orthostatic hypotension or tachycardia (2).
  • Cardiovascular agentsCardiovascular agents: Based on case reports, oral ingestion may cause an explosive illness with orthostatic hypotension or tachycardia (2).
  • Drugs that cause rhabdomyolysisDrugs that cause rhabdomyolysis: Based on case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4).
  • Drugs that may lower seizure thresholdDrugs that may lower seizure threshold: Based on case reports, oral ingestion may cause an explosive illness with seizures and convulsions (3; 7; 5; 6), neurologic lethargy (2), or unconsciousness (5; 2) that may lead to death (1; 7; 2; 6).
  • Nephrotoxic agentsNephrotoxic agents: According to case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4) or marked metabolic acidosis (5; 6).
  • Renally eliminated drugsRenally eliminated drugs: Based on case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4), marked metabolic acidosis (5; 6), or acute renal failure (3; 4).
  • SedativesSedatives: Based on case reports, oral ingestion may cause an explosive illness with neurologic lethargy (2), or unconsciousness (5; 2) that may lead to death (1; 7; 2; 6).

    • Water hemlock/Herb/Supplement Interactions:

  • AnticonvulsantsAnticonvulsants: Based on case reports, oral ingestion may cause an explosive illness with seizures and convulsions (3; 7; 5; 6), neurologic lethargy (2), or unconsciousness (5; 2) that may lead to death (1; 7; 2; 6).
  • Cardiac glycosidesCardiac glycosides: Based on case reports, oral ingestion may cause an explosive illness with orthostatic hypotension or tachycardia (2).
  • Cardioactive herbsCardioactive herbs: Based on case reports, oral ingestion may cause an explosive illness with orthostatic hypotension or tachycardia (2).
  • Herbs that lower seizure thresholdHerbs that lower seizure threshold: Based on case reports, oral ingestion may cause an explosive illness with seizures and convulsions (3; 7; 5; 6), neurologic lethargy (2), or unconsciousness (5; 2) that may lead to death (1; 7; 2; 6).
  • PotassiumPotassium: Based on case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4).
  • Nephrotoxic agentsNephrotoxic agents: According to case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4) or marked metabolic acidosis (5; 6).
  • Renally eliminated herbs and supplementsRenally eliminated herbs and supplements: Based on case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4), marked metabolic acidosis (5; 6), or acute renal failure (3; 4).
  • SedativesSedatives: Based on case reports, oral ingestion may cause an explosive illness with neurologic lethargy (2), or unconsciousness (5; 2) that may lead to death (1; 7; 2; 6).

    • Water hemlock/Food Interactions:

  • Insufficient available evidence.

    • Water hemlock/Lab Interactions:

  • Arterial blood gas measurementArterial blood gas measurement: According to case reports, oral ingestion may cause an explosive illness with marked metabolic acidosis (5; 6).
  • Blood urea nitrogen (BUN)Blood urea nitrogen (BUN): According to case reports, oral ingestion may cause an explosive illness with marked metabolic acidosis (5; 6) or acute renal failure (3; 4).
  • Plasma electrolyte levelsPlasma electrolyte levels: According to case reports, oral ingestion may cause an explosive illness with marked metabolic acidosis (5; 6) or acute renal failure (3; 4).
  • Serum creatine levelsSerum creatine levels: Based on case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4) or marked metabolic acidosis (5; 6).
  • Serum potassium levelsSerum potassium levels: Based on case reports, oral ingestion may cause an explosive illness with rhabdomyolysis (3; 4).