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Parkinson?s Drugs
Antiparkinson Agents/Nutrient Depletion:
Iron
Iron: Based on human study, iron may reduce the amount of levodopa absorbed by forming chelates with levodopa (Sinemet?) (
2920496
). Secondary sources cite that until further research is available, doses of levodopa and iron should be separated.
Niacin/Niacinamide:
Niacin/Niacinamide: Based on human study, L-dopa, benserazide, and carbidopa may deplete niacin through reduced synthesis of nicotinamide coenzymes from tryptophan and increased urinary excretion of N1-methyl-nicotinamide (
477187
).
Potassium:
Potassium: Based on reviews, L-dopa may increase urinary excretion of potassium, which may lead to hypokalemia (
851038
,
4927447
).