Piper nigrum

Black pepper/Nutrient Depletions:

  • GlucoseGlucose: In alloxan-induced diabetic animals, an aqueous extract of black pepper seeds resulted in a lowering of blood sugar (44). In animal study, piperine lowered the serum levels of glucose (106).
  • LipidsLipids: In animals, piperine reduced plasma lipids and lipoproteins levels, increased levels of HDL-cholesterol, and improved levels of apo A-1 and apo B (43; 44) and inhibited acyl-CoA:cholesterol acyltransferase (ACAT) activity (209; 210).