Soy isoflavones

Isoflavones/Nutrient Depletion:

  • AlbuminAlbumin: In human research, following soy protein consumption, urinary albumin excretion was reported to be negatively correlated with total plasma isoflavones (96).
  • CholesterolCholesterol: Purified isoflavones did not have an reducing effect on plasma lipids in some human research (47; 61; 98), although increases in HDL (and HDL3) cholesterol and apolipoprotein A-1 have been noted (99; 90; 70; 100; 101; 4), as have reductions in total cholesterol (65), triglycerides (66; 67; 68), and LDL cholesterol (69; 70; 71; 72; 4), and changes in LDL size to be less atherogenic (72), in other studies.
  • GlucoseGlucose: Use of isoflavone supplements in women decreased fasting glucose (46).
  • PhosphatePhosphate: The estrogen-like effects of isoflavones may theoretically affect phosphate levels. Further research is needed before a firm conclusion may be drawn.